101071-96-9

Basic information

• Product Name: 8-BroMo-7-ethyl-3,7-dihydro-3-Methyl-1H-purine-2,6-dione
• Synonyms: 8-BroMo-7-ethyl-3,7-dihydro-3-Methyl-1H-purine-2,6-dione;8-bromo-7-ethyl-3-methylpurine-2,6-dione
• CAS NO: 101071-96-9
• Molecular Formula: C8H9BrN4O2
• Molecular Weight: 273.08666
• Product Categories: Aromatics, Heterocycles, Metabolites & Impurities
• Mol File: 101071-96-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-BroMo-7-ethyl-3,7-dihydro-3-Methyl-1H-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 8-BroMo-7-ethyl-3,7-dihydro-3-Methyl-1H-purine-2,6-dione(101071-96-9)
• EPA Substance Registry System: 8-BroMo-7-ethyl-3,7-dihydro-3-Methyl-1H-purine-2,6-dione(101071-96-9)

Safety Data

• Hazardous Substances Data: 101071-96-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
8-Bromo-7-ethyl-3,7-dihydro-3-methyl-1H-purine-2,6-dione is used as a bronchodilator for the treatment of respiratory conditions. It helps to relax and widen certain breathing passages of the lungs, providing relief from asthma and other respiratory disorders.
Additionally, a large number of derivatives of this compound have been found to possess adenosine receptor antagonist properties. This characteristic makes them valuable in the development of drugs targeting various physiological and pathological processes, such as cardiovascular diseases, neurodegenerative disorders, and cancer.

Upstream product

• 93703-24-3 3-methyl-8-bromoxanthine 
• 75-03-6 ethyl iodide 

Relevant articles and documents

Oxidative addition of a 8-bromotheobromine derivative to d10metals

Reaction of 8-bromo-7-ethyl-3-methylxanthine 1 with zerovalent group 10 metal complexes gave via an oxidative addition of the C-Br bond the neutral complexes trans-[2] (M = Pd) and trans-[3] (M = Pt) bearing a theobromine-derived azolato ligand. While the oxidative addition to [Pd0(PPh3)4] gave exclusively trans-[2], the reaction with the more substitution-inert [Pt0(PPh3)4] yielded after 1 day the kinetic product cis-[3], which was converted under heating for a total of 3 days completely into the thermodynamically more stable complex trans-[3]. Treatment of trans-[2], trans-[3] or the mixture of cis-/trans-[3] with the proton source HBF4·Et2O led to complexes trans-[4]BF4, trans-[5]BF4 and a mixture of cis/trans-[5]BF4 with retention of the original ratio of cis to trans, respectively. The molecular structures of the azolato complexes trans-[2] and trans-[3] and of the theobromine derived pNHC complexes trans-[4]BF4 and trans-[5]BF4 have been determined by X-ray diffraction studies.

XANTHINE ANALOGS AS POTENT ANTI-WEST NILE VIRAL AGENTS

The present disclosure is concerned with xanthine analogs, methods of making xanthine analogs, and methods of treating West Nile virus using these analogs. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.