101093-93-0

Basic information

• Product Name: 2-(2-PHENOXY-ETHOXY)-BENZOIC ACID
• Synonyms: Benzoic acid, 2-(2-phenoxyethoxy)-
• CAS NO: 101093-93-0
• Molecular Formula: C₁₅H₁₄O₄
• Molecular Weight: 258.27
• Mol File: 101093-93-0.mol

Chemical Properties

• Boiling Point: 446.7°C at 760 mmHg
• Flash Point: 169.1°C
• Appearance: /
• Density: 1.224g/cm³
• Vapor Pressure: 9.22E-09mmHg at 25°C
• Refractive Index: 1.585
• CAS DataBase Reference: 2-(2-PHENOXY-ETHOXY)-BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-PHENOXY-ETHOXY)-BENZOIC ACID(101093-93-0)
• EPA Substance Registry System: 2-(2-PHENOXY-ETHOXY)-BENZOIC ACID(101093-93-0)

Safety Data

• Hazardous Substances Data: 101093-93-0(Hazardous Substances Data)

Usage

Physical appearance

White crystalline solid The compound appears as a white, crystalline solid substance.

Solubility

Insoluble in water, soluble in organic solvents It does not dissolve well in water but can dissolve in certain organic solvents.

Uses

Pharmaceutical, agricultural, and dye production 2-(2-phenoxy-ethoxy)-benzoic acid is a key ingredient in the manufacturing of various pharmaceuticals, agricultural chemicals, and dyes.

Herbicide and plant growth regulator

It acts as a herbicide, controlling weeds, and as a plant growth regulator, managing plant growth.

Medicinal properties

Anti-inflammatory and analgesic The compound exhibits properties that help reduce inflammation and relieve pain.

Aromatic properties

Perfume and fragrance manufacturing Due to its aromatic properties, 2-(2-phenoxy-ethoxy)-benzoic acid is used in the production of perfumes and fragrances.

Safety precautions

Handle with caution and follow proper safety protocols This chemical compound may pose potential hazards and risks, so it is essential to handle it with care and follow appropriate safety measures.

InChI:InChI=1/C15H14O4/c16-15(17)13-8-4-5-9-14(13)19-11-10-18-12-6-2-1-3-7-12/h1-9H,10-11H2,(H,16,17)

Upstream product

• 589-10-6 phenoxyethyl bromide 
• 119-36-8 methyl salicylate 
• 123470-88-2 ethyl 2-(2-phenoxyethoxy)benzoate 
• 124-38-9 carbon dioxide 
• 104-66-5 1,2-diphenoxyethane 
• 118-61-6 2-hydroxy-benzoic acid ethyl ester 
• 2665-64-7 methyl 2-(2-phenoxyethoxy)benzoate 

Downstream Products

• 1094024-70-0 N',N'-dimethyl-2-(2-phenoxyethoxy)benzohydrazide 
• 1094023-99-0 N'-[1-imidazol-1-yl-1-[2-(2-phenoxyethoxy)phenyl]methylidene]-N,N-dimethylhydrazine 

Relevant articles and documents

AZOLYLMETHYLENEHYDRAZINE DERIVATIVE AND USE THEREOF

An azolylmethylidenehydrazine derivative represented by the formula (I) wherein Ar is an aryl group optionally having substituent(s), a heteroaryl group optionally having substituent(s) or a heteroaryl group optionally having substituent(s), R1

Inhibitors of the protease from human immunodeficiency virus: Synthesis, enzyme inhibition, and antiviral activity of a series of compounds containing the dihydroxyethylene transition-state isostere

A number of potential HIV protease inhibitory peptides that contain the dihydroxyethylene isostere were prepared and evaluated for their enzyme binding affinity and antiviral activity in cell cultures. From the template of a previously reported active peptide A, modifications at the N- and C- terminal groups were assessed for potential maintenance of good inhibitory activity of the resulting peptides. Among the active peptides found, peptide XVIII exhibited potent enzyme inhibitory activity. Interestingly, the previously reported, effective 1(S)-amino-2(R)-hydroxyindan C-terminal group for the preparation of very active HIV protease inhibitory peptides could not be applied to the template of peptide XVIII. Molecular modeling of peptide XVIII was studied using the X-ray crystal structure of peptide A as a starting point in order to study the likely conformation of peptide XVIII in the active-site cleft. Relative binding conformations of peptide A and XVIII were obtained, although the reason for poor binding affinity for a number of congeneric peptides in this report was not straightforwardly apparent. More importantly, however, peptide XVIII was found to exhibit more effective antiviral activity in the HIV-1/PBMC assay than the reference peptide A which was previously reported to be approximately equal in efficacy to the reverse transcriptase inhibitor AZT in this assay.