cas 1012059-54-9, 1H-IMidazo[4,5-c]pyridin-4-aMine, 2-[(6-broMo-1,3-benzodioxol-5-yl)thio]-1-[(4-Methoxyphenyl)Methyl] | Articles data ｜lookchem

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1012059-54-9

Articles about 1012059-54-9Total 5 be found

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Fused Amino Pyridines for the Treatment of Lung Cancer
The present invention relates to the use of compounds with fused amino pyridine core for the treatment of malignancies associated with brain and lung. The oral administration of compounds of the instant application results in effective brain penetration and provides for non-intrusive treatment of brain and lung tumors.
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Paragraph 0154

(2016/11/17)

Therapeutic compounds and uses thereof
The invention provides novel therapeutic compounds, pharmaceutical compositions comprising these compounds, and methods for using these compounds and compositions to treat diseases and disorders such as cancer.
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(2011/10/03)

FUSED AMINO PYRIDINES FOR THE TREATMENT OF BRAIN TUMORS
The present invention relates to the use of compounds with fused amino pyridine core for the treatment of malignancies associated with brain and lung. The oral administration of compounds of the instant application results in effective brain penetration and provides for non-intrusive treatment of brain and lung tumors.
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(2010/08/07)

HSP90 Inhibitors Containing a Zinc Binding Moiety
The present invention relates to HSP90 inhibitors and their use in the treatment of cell proliferative diseases such as cancer. The said derivatives may further act as HDAC inhibitors.
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Page/Page column 44

(2008/12/08)

FUSED AMINO PYRIDINE AS HSP90 INHIBITORS
The present invention relates to HSP90 inhibitors containing fused amino pyridine core that are useful as inhibitors of HSP90 and their use in the treatment of HSP90 related diseases and disorders such as cancer, an autoimmune disease, or a neurodegenerative disease.
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Page/Page column 44

(2008/12/08)

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Chemical Properties

Boiling Point: 700.2±70.0 °C(Predicted)
Density: 1.67±0.1 g/cm3(Predicted)
PKA: 5.95±0.30(Predicted)
PSA: 110.45000
LogP: 4.64290

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