101234-67-7

Basic information

• Product Name: 1(4H)-PYRIDINEACETIC ACID, 4-OXO-, DIPHENYLMETHYL ESTER
• Synonyms: 1(4H)-PYRIDINEACETIC ACID, 4-OXO-, DIPHENYLMETHYL ESTER
• CAS NO: 101234-67-7
• Molecular Formula: C₂₀H₁₇NO₃
• Molecular Weight: 319.35
• Mol File: 101234-67-7.mol

Chemical Properties

• Boiling Point: 468.7°C at 760 mmHg
• Flash Point: 237.3°C
• Appearance: /
• Density: 1.215g/cm³
• Vapor Pressure: 5.85E-09mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: 1(4H)-PYRIDINEACETIC ACID, 4-OXO-, DIPHENYLMETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1(4H)-PYRIDINEACETIC ACID, 4-OXO-, DIPHENYLMETHYL ESTER(101234-67-7)
• EPA Substance Registry System: 1(4H)-PYRIDINEACETIC ACID, 4-OXO-, DIPHENYLMETHYL ESTER(101234-67-7)

Safety Data

• Hazardous Substances Data: 101234-67-7(Hazardous Substances Data)

Usage

Type of Compound

Synthetic organic compound

Uses

Precursor in the synthesis of pharmaceuticals and agrochemicals
Reagent in organic chemistry reactions

Physical Appearance

Pale yellow powder

Solubility

Soluble in organic solvents such as methanol, ethanol, and acetone

Safety Precautions

Harmful if ingested or inhaled
May cause skin and eye irritation upon contact

Handling

Should be handled with care to avoid ingestion, inhalation, or skin/eye contact

InChI:InChI=1/C20H17NO3/c22-18-11-13-21(14-12-18)15-19(23)24-20(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,20H,15H2

Upstream product

• 108-96-3 4-pyridone 
• 90849-28-8 chloro-acetic acid benzhydryl ester 
• 626-64-2 pyridin-4-ol 
• 79287-72-2 diphenylmethyl bromoacetate 

Downstream Products

• 101234-68-8 1-(diphenylmethoxycarbonylmethyl)-4-thiopyridone 

Relevant articles and documents

Synthesis and biological activity of 3-(N-substituted pyridinium-4-thiomethyl)-7α-formamido cephalosporins

The synthesis and antibacterial activity of a series of 3-(1-substituted pyridinium-4-thiomethyl)-7α-formamido cephalosporins is described. All the derivatives showed good potency and stability to bacterial β-lactamases. The antibacterial efficacy seen with the N-alkyl pyridinium substituents was enhanced by the introduction of a catecholic side chain at C-7 and by preparation of N-(substituted amino)pyridinium derivatives.

Cephalosporin derivatives

This is a class of antibacterial compounds of the formula: STR1 wherein Y is straight or branched alkyl or alkenyl chain, cycloalkanomethyl of 3-6 carbon atoms, each group being optionally substituted by halogen, or a group STR2 wherein n is 0 or an integer of 1-3, A is a group --COR3 wherein R3 is hydroxy, a group STR3 wherein R4 and R5, which may be the same or different, are hydrogen or alkyl of 1-5 carbon atoms, a group STR4 or a 5- or 6-membered heterocyclic group containing nitrogen and/or sulfur, and R1 and R2, which may be the same or different, are hydrogen, alkyl of 1-5 carbon atoms, or R1 and R2 may be combined together to form cycloalkylidene of 3-5 carbon atoms, and Z is a group of the formula: STR5 wherein m is 0 or an integer of 3-5, R6 is hydrogen or alkyl of 1-3 carbon atoms, and R7, when m is an integer of 3-5, is alkyl of 1-5 carbon atoms, alkenyl, cyclopropyl, a group --(CH2)p B wherein p is 0 or an integer of 1-3 and B is amino, alkyl-substituted amino, hydroxy, carboxy, carbamoyl, trifluoromethyl, sulfonic acid, sulfonic acid amide, alkylthio or cyano or, when m is 0, is alkyl of 1-5 carbon atoms, which may optionally be substituted by halogen, alkenyl, a group STR6 wherein R8 is hydrogen, alkyl of 1-4 carbon atoms or phenyl, or cyclopropyl, and a salt thereof.