101544-49-4Relevant articles and documents
Indole-Phenol Bioisosterism. Synthesis and Antihypertensive Activity of a Pyrrolo Analogue of Labetalol
Asselin, Andre A.,Humber, Leslie G.,Crosilla, Danilo,Oshiro, George,Wojdan, Alexandra,et al.
, p. 1009 - 1015 (2007/10/02)
The synthesis of 5-ethyl>-1H-indole-7-carboxamide, 5, a pyrrolo analogue of labetalol, is described.Compound 5 was found to reduce blood pressure in spontaneously hypertensive rats with an ED50 of 5 mg/kg po, wit
5-Indolyl substituted aminoethanols
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, (2008/06/13)
Herein is disclosed bicyclic-substituted aminoethanol derivatives, therapeutically acceptable acid addition salts thereof, processes for their preparation, methods of using the derivatives and pharmaceutical compositions. The derivatives are useful for tr