76139-03-2Relevant articles and documents
N-SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES
-
Page/Page column 122, (2010/02/12)
This invention relates to compounds of the formula 1 wherein R1, R2, R7, R8, R9, U, V, Z, A, W, X, M, E, L, T and D are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system and other disorders.
5-heteroyl indole derivatives
-
, (2008/06/13)
Compounds of the formula STR1 which are useful in treating migraine and other disorders, and intermediates used in the preparation of said compounds.
Indole-Phenol Bioisosterism. Synthesis and Antihypertensive Activity of a Pyrrolo Analogue of Labetalol
Asselin, Andre A.,Humber, Leslie G.,Crosilla, Danilo,Oshiro, George,Wojdan, Alexandra,et al.
, p. 1009 - 1015 (2007/10/02)
The synthesis of 5-ethyl>-1H-indole-7-carboxamide, 5, a pyrrolo analogue of labetalol, is described.Compound 5 was found to reduce blood pressure in spontaneously hypertensive rats with an ED50 of 5 mg/kg po, wit