10185-02-1

Basic information

• Product Name: 7-HYDROXY-3-(2-HYDROXYETHYL)-4-METHYL-2H-CHROMEN-2-ONE
• Synonyms: 7-HYDROXY-3-(2-HYDROXYETHYL)-4-METHYL-2H-CHROMEN-2-ONE
• CAS NO: 10185-02-1
• Molecular Formula: C12H12O4
• Molecular Weight: 220.22
• Mol File: 10185-02-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-HYDROXY-3-(2-HYDROXYETHYL)-4-METHYL-2H-CHROMEN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-HYDROXY-3-(2-HYDROXYETHYL)-4-METHYL-2H-CHROMEN-2-ONE(10185-02-1)
• EPA Substance Registry System: 7-HYDROXY-3-(2-HYDROXYETHYL)-4-METHYL-2H-CHROMEN-2-ONE(10185-02-1)

Safety Data

• Hazardous Substances Data: 10185-02-1(Hazardous Substances Data)

Upstream product

• 156760-77-9 C₁₃H₂₂O₅ 
• 108-46-3 recorcinol 
• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 

Relevant articles and documents

Magnetic nanoparticles functionalized ethane sulfonic acid (MNESA): as an efficient catalyst in the synthesis of coumarin derivatives using Pechmann condensation under mild condition

This paper reports an efficient heterogeneous catalyst based on sulfonic acid functionalization of magnetic nanoparticles. This new catalyst was prepared using the reaction between magnetic nanoparticles and sodium 2-bromoethane-1-sulfonate. Magnetic nanoparticles functionalized ethane sulfonic acid (MNESA) was found as efficient catalyst for the synthesis of coumarin derivatives using Pechmann condensation under mild condition. This reaction was catalyzed by MNESA under solvent-free condition at 90?°C, to give the corresponding products in excellent yields. The catalyst is easily separated from the reaction condition and can be reused for several times with consistence in the activity.

Silica supported boric tri-sulfuric anhydride as a novel and efficient catalyst for solvent-free synthesis of coumarins via Pechmann condensation

It is found that silica supported boric trisulfuric anhydride (BTSA.SiO2) is a novel, suitable and versatile catalyst for efficient and clean synthesis of coumarins via Pechmann cyclocondensation under mild and solvent-free conditions. Different kinds of

First total synthesis of ocimarin

A facile approach for the first synthesis of ocimarin, naturally occurring coumarins, was developed by employing a cerium (III) chloride heptahydrate-catalyzed Pechmann condensation of phenols and β-keto esters in a solvent-free system as key step, by which ocimarin was achieved by three steps starting from acetylacetic ether and resorcinol with total yield 23.2%. All structures of new compounds were confirmed by IR, 1H NMR and MS.