- Preparation method of 2-fluoro-2-alkyloxy trifluoropropionate
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The invention discloses a preparation method of 2-fluoro-2-alkyloxy trifluoropropionate. In the presence of an organic alkali and/or an inorganic alkali, hexafluoropropylene oxide and alkyl alcohols carry out reactions to obtain corresponding 2-fluoro-2-alkyloxy trifluoropropionate. The provided method has the advantages of suitable reaction temperature, high reaction yield, good selectivity, little amount of waste solid, waste water, and waste gas, and easiness for industrialization. The prepared 2-fluoro-2-alkyloxy trifluoropropionate can be used as a trifluoromethylation reagent for the synthesis of novel medicines and pesticides.
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Paragraph 0024; 0025; 0026; 0027; 0028; 0029; 0034; 0035
(2017/08/29)
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- Hexafluoropropylene oxide-alcohol: A convenient system for silica dissolution
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A new method of silica dissolution is described. It involves the formation of a stable SiF4 n ROH complex (1, 1a) just from SiO2 and anhydrous alcoholic HF generated in situ from commercially available hexafluoropropene oxide. Alcoholic SiF4 complexes can be easily converted to different organosilicon compounds of the type SiF4L 2 and (LH)2SiF6 [L = 1,10-phenantroline (2a), 2,2'-dipyridyl (2b), Me2SO (2c), pyridine (2d), triethanolamine (3a)]. Different silica-containing compounds can be used in this strategysilicagel, sand, alumosilicates, and even rice husk. Copyright Taylor & Francis Group, LLC.
- Lermontov, Sergey A.,Malkova, Alena N.,Lermontova, El'mira Kh.,Churakov, Andrei V.
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experimental part
p. 178 - 188
(2011/04/22)
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- Formylimine versus Isocyanate - an Unusual Tautomerism of a Trifluoroalanine Derivative
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The intermediate 7a formed by hydrogen chloride elimination of 6 can easily tautomerize to the isolable isocyanate 7b.Depending on the reaction conditions nucleophiles react with 7a and 7b to give the corresponding products 8 or 9, respectively. Key Words
- Matthies, Dieter,Siewers, Stefan
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p. 159 - 162
(2007/10/02)
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- UNUSUAL REACTION CHEMISTRY IN THERMAL DECOMPOSITION OF ALKALI METAL 2-ALKOXY-2,3,3,3-TETRAFLUOROPROPIONATE SALTS
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Pyrolyses of several salts ROCF(CF3)CO2(-)M(+) (R=Me, Et, CF3CH2; M=Na, K, Cs) have been studied.The reaction chemistry shows highly unusual dependence on the nature of the alkoxy substituent and the metal cation.Product distribution are described along with some proposed mechanisms.
- Pellerite, Mark J.
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