101976-91-4

Basic information

• Product Name: [(1S,2R)-2-hydroxycyclohexyl]acetonitrile
• CAS NO: 101976-91-4
• Molecular Formula: C₈H₁₃NO
• Molecular Weight: 139.1949
• Mol File: 101976-91-4.mol

Chemical Properties

• Boiling Point: 288.3°C at 760 mmHg
• Flash Point: 128.2°C
• Density: 1.035g/cm³
• Vapor Pressure: 0.000262mmHg at 25°C
• Refractive Index: 1.484
• CAS DataBase Reference: [(1S,2R)-2-hydroxycyclohexyl]acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: [(1S,2R)-2-hydroxycyclohexyl]acetonitrile(101976-91-4)
• EPA Substance Registry System: [(1S,2R)-2-hydroxycyclohexyl]acetonitrile(101976-91-4)

Safety Data

• Hazardous Substances Data: 101976-91-4(Hazardous Substances Data)

Upstream product

• 286-20-4 cyclohexane-1,2-epoxide 
• 75-05-8 acetonitrile 
• 42185-27-3 2-(cyanomethyl)cyclohexanone 
• 99749-00-5 lithioacetonitrile 

Downstream Products

• 90226-51-0 (+/-)-trans-2-(2-amino-ethyl)-cyclohexanol 
• 5426-58-4 trans-(2-hydroxy-cyclohexyl)acetic acid 
• 74629-91-7 (1R,2S,R)-trans-2-(Cyanomethyl)cyclohexyl N-<1-(1-Naphthyl)-ethyl>carbamate 
• 74708-29-5 (1S,2R,R)-trans-2-(Cyanomethyl)cyclohexyl N-<1-(1-Naphthyl)-ethyl>carbamate 
• 24871-12-3 trans-hexahydro-2(3H)-benzofuranone 
• 101859-26-1 (1R*,2S*)-((2-tert-butyldimethylsilyl)-oxy)cyclohexaneacetonitryle 
• 101859-27-2 (2-t-butyldimethylsiloxy)cyclohexylacetaldehyde 
• 101858-81-5 (1R,2S)-2-((E)-4-Benzyloxy-but-2-enyl)-cyclohexanol 
• 101859-31-8 (1R*,2S*,(2E))-2-((tert-butyldimethylsilyl)oxy)cyclohexane-3-methyl-2-buten-4-ol 
• 101858-82-6 (1R*,3S*,4R*,6S*)-3-((benzyloxy)methyl)-4-iodo-2-oxabicyclo<4.4.0.>decane 
• 101858-94-0 (1R*,3S*,4R*,6S*)-3-((benzyloxy)methyl)-2-oxabicyclo<4.4.0>dec-4-ol 
• 101859-57-8 (1S,2R)-2-((E)-4-Benzyloxy-3-methyl-but-2-enyl)-cyclohexanol 
• 101858-88-2 (1R*,6S*)-8-(2-(benzyloxy)-1-iodoethyl)-7-oxabicyclo<4.3.0>nonane 
• 101859-28-3 (E)-4-[(1S,2R)-2-(tert-Butyl-dimethyl-silanyloxy)-cyclohexyl]-but-2-enoic acid methyl ester 

Relevant articles and documents

Enantiomerically Pure Lactones. 2. Approaches to Cis or Trans Multicyclic Lactones

Enantiomerically pure bicyclic lactones 1-3 and tricyclic lactones 4 and 5 have been prepared by either of two procedures, each hinging upon the liquid chromatographic seperation of rationally selected diastereomeric derivatives.After seperation, the diastereomers are converted by a simple high-yield reaction sequence to the enantiomeric multiring lactones, none of which has been previously reported in optically active form. The relative strengths and weaknesses of each approach are discussed.Lactones 4 and 5 were α-methylated, these derivatives being suitable for the determination of enantiomeric purity and absolute configuration using the chiral solvating agent (S)-(+)-2,2,2-trifluoro-1-(9-anthryl)ethanol.