10200-25-6

Basic information

• Product Name: N-(2,4-Dinitrophenyl)proline
• Synonyms: N-(2,4-Dinitrophenyl)proline
• CAS NO: 10200-25-6
• Molecular Formula: C₁₁H₁₁N₃O₆
• Molecular Weight: 281.22
• Product Categories: pharmacetical
• Mol File: 10200-25-6.mol

Chemical Properties

• Boiling Point: 531°C at 760 mmHg
• Flash Point: 275°C
• Appearance: /
• Density: 1.563g/cm³
• Vapor Pressure: 4.17E-12mmHg at 25°C
• Refractive Index: 1.65
• CAS DataBase Reference: N-(2,4-Dinitrophenyl)proline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,4-Dinitrophenyl)proline(10200-25-6)
• EPA Substance Registry System: N-(2,4-Dinitrophenyl)proline(10200-25-6)

Safety Data

• Hazardous Substances Data: 10200-25-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H11N3O6/c15-11(16)9-2-1-5-12(9)8-4-3-7(13(17)18)6-10(8)14(19)20/h3-4,6,9H,1-2,5H2,(H,15,16)

Upstream product

• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 147-85-3 L-proline 
• 70-34-8 2,4-Dinitrofluorobenzene 
• 609-36-9 rac-Pro-OH 
• 147-85-3 L-proline 
• 610-31-1 1,2,4-trinitrobenzene 

Downstream Products

• 117342-48-0 5-chloro-2-(2,4-dinitro-anilino)-valeric acid 
• 99860-32-9 2-chloro-5-(2,4-dinitro-anilino)-valeric acid 

Relevant articles and documents

Synthesis of tri- and tetracyclic condensed quinoxalin-2-ones fused across the C-3 - N-4 bond

We have studied the preparation of some fused quinoxalinones by Stevens rearrangement of a spiro-quinoxaline-derived ammonium ylide or by treatment of N-(2,4-dinitrophenyl)-and N-(2-nitrophenyl)imino acids with different reducing agents. We have reinvestigated and clarified some related processes found in the literature starting from imino acids derivatives. Additional reactions of the fused quinoxalinones, as well as the useful dehydrogenation/decarboxylation of some easily available 1-arylindoline-2-carboxylic acids to the corresponding 1-arylindoles, are also reported. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.

1,2,4-TRINITROBENZENE AS A THIOL REAGENT

The 2,4-dinitrophenylation of thiol or amino group with 1,2,4-trinitrobenzene proceeded quantitatively at pH 8.5 and 30 deg C.The rate of S-dinitrophenylation was ca. 1E4 times faster than that of N-dinitrophenylation.So this reaction can be used for both the determination of thiol even in the presence of large excess amine and the specific modification of thiol in proteins.