1023742-13-3

Basic information

• Product Name: O-(2-tert-butoxyethyl)hydroxylaMine
• Synonyms: O-(2-tert-butoxyethyl)hydroxylaMine;EOS-60396
• CAS NO: 1023742-13-3
• Molecular Formula: C₆H₁₅NO₂
• Molecular Weight: 133.1888
• Mol File: 1023742-13-3.mol

Chemical Properties

• Boiling Point: 186.481 °C at 760 mmHg
• Flash Point: 63.873 °C
• Appearance: /
• Density: 0.925 g/cm³
• PKA: 4.28±0.70(Predicted)
• CAS DataBase Reference: O-(2-tert-butoxyethyl)hydroxylaMine(CAS DataBase Reference)
• NIST Chemistry Reference: O-(2-tert-butoxyethyl)hydroxylaMine(1023742-13-3)
• EPA Substance Registry System: O-(2-tert-butoxyethyl)hydroxylaMine(1023742-13-3)

Safety Data

• Hazardous Substances Data: 1023742-13-3(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
O-(2-tert-butoxyethyl)hydroxylaMine is used as a reagent in organic synthesis for its ability to facilitate the preparation of pharmaceuticals and agrochemicals. Its unique structure allows for specific reactions that are crucial in the synthesis of these compounds.
Used in Pharmaceutical Industry:
In the Pharmaceutical Industry, O-(2-tert-butoxyethyl)hydroxylaMine is used as an intermediate in the production of various drugs. Its role in the synthesis process is vital for creating the desired medicinal compounds.
Used in Agrochemical Industry:
Similarly, in the Agrochemical Industry, O-(2-tert-butoxyethyl)hydroxylaMine is utilized as an intermediate for the synthesis of agrochemicals, contributing to the development of products used in agriculture.
Used in Chemical Production:
O-(2-tert-butoxyethyl)hydroxylaMine is also used as an intermediate in the production of other chemicals such as rubber antioxidants and corrosion inhibitors, highlighting its broad application across different chemical sectors.
Safety Note:
It is important to handle O-(2-tert-butoxyethyl)hydroxylaMine with care due to its potential to cause irritation to the skin, eyes, and respiratory system. Proper safety measures should be taken to minimize exposure and ensure safe usage.

Upstream product

• 7580-85-0 tert-butyl glycidyl ether 
• 870243-67-7 2-(2-tert-butoxy-ethoxy)-isoindole-1,3-dione 

Downstream Products

• 1604812-70-5 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid-(2-tert-butoxyethoxy)amide 
• 1150098-27-3 6-fluoro-7-(2-fluoro-4-iodo-phenylamino)-5-oxo-1,2,3,5-tetrahydro-indolizine-8-carboxylic acid (2-tert-butoxy-ethoxy)-amide 
• 1035556-52-5 3-(2-tert-butoxyethoxy)-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione 
• 1026989-57-0 N-(2-tert-butoxyethoxy)-3-ethyl-6-(2-fluoro-4-iodophenylamino)-1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 
• 1026989-34-3 N-(2-tert-butoxyethoxy)-6-(2-chloro-4-iodophenylamino)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 

Relevant articles and documents

Method for synthesizing azanol

The invention relates to a hydroxylamine synthesis method. The hydroxylamine synthesis method comprises the following steps: (A) enabling alcohol to react with alkyl sulfonyl halide in the presence of an acid-binding agent to obtain sulphonate; (B) enabling the obtained sulphonate in the step (A) to react with N-hydroxycyclodiimide in the presence of alkali to generate alkylate of the N-hydroxycyclodiimide; and (C) enabling the alkylate obtained in the step (B) to react with an aminolysis reagent or a hydrazinolysis reagent to obtain the hydroxylamine. The method is high in yield and suitable for large-scale industrial hydroxylamine synthesis.

KINASE INHIBITORS AS THERAPEUTIC AGENTS

A compound or pharmaceutically acceptable salts thereof of Formula (I) wherein the substituents are as defined herein, which are useful as kinase inhibitors.