1604812-70-5 Usage
General Description
6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid-(2-tert-butoxyethoxy)amide, also known as BFB-FA-TPA, is a chemical compound with potential pharmaceutical applications. It is a carboxylic acid amide that contains a benzimidazole ring and fluorophenylamino and fluoro groups. The presence of these functional groups suggests that BFB-FA-TPA may have bioactive properties, potentially exhibiting anticancer, antiviral, or antibacterial activity. Additionally, the tert-butoxyethoxy moiety provides solubility and stability to the compound, making it suitable for drug formulation. Further research is warranted to fully explore the pharmacological potential of BFB-FA-TPA and its efficacy in various therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1604812-70-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,0,4,8,1 and 2 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1604812-70:
(9*1)+(8*6)+(7*0)+(6*4)+(5*8)+(4*1)+(3*2)+(2*7)+(1*0)=145
145 % 10 = 5
So 1604812-70-5 is a valid CAS Registry Number.
1604812-70-5Relevant articles and documents
Synthesizing method for binimetinib
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, (2016/10/24)
The invention discloses a synthesizing method for binimetinib. The method comprises the steps that 2,3,4-trifluoro-5-nitrobenzoic acid and O-(2-tert-butoxy ethyl)hydroxylamine are subjected to a condensation reaction, and obtained N-(2-tert-butoxy ethyoxyl)-2,3,4-trifluoro-5-nitrobenzamide and ammonium hydroxide are subjected to an ammonolysis reaction; obtained N-(2-tert-butoxy ethyoxyl)-2,4-diamino-3-fluoro-5-nitrobenzamide and formic acid are subjected to a ring-closure reaction in a Pearlman's catalyst; obtained N-(2-tert-butoxy ethyoxyl)-6-amino-7-fluoro-3H-benzimidazole-5-formamide and 4-bromo-2-fluoro-1-iodobenzene are subjected to a substitution reaction; obtained N-(2-tert-butoxy ethyoxyl)-6-[(4-bromo-2-fluoro-phenyl)amino]-7-fluoro-3H-benzimidazole-5-formamide is firstly subjected to a methylation reaction with methyl iodide and then subjected to a deprotection reaction with phosphoric acid, and binimetinib is obtained. The synthesizing method is short in route, operation is simplified, cost is low, and the synthesizing method is environmentally friendly and suitable for industrial production.
