102402-46-0 Usage
General Description
2-amino-2-phosphono-cyclohexane-1-carboxylic acid, also known as AP6, is a synthetic amino acid derivative with the chemical formula C7H12NO5P. It is a potent and selective antagonist of the NMDA receptor, which plays a critical role in synaptic plasticity and memory function. AP6 has been studied for its potential therapeutic applications in the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's. It has also been used as a research tool to study the role of NMDA receptors in various physiological and pathological processes in the brain. Additionally, AP6 is known to be a useful pharmacological tool for investigating the mechanisms of excitatory neurotransmission and synaptic plasticity in the central nervous system.
Check Digit Verification of cas no
The CAS Registry Mumber 102402-46-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,4,0 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 102402-46:
(8*1)+(7*0)+(6*2)+(5*4)+(4*0)+(3*2)+(2*4)+(1*6)=60
60 % 10 = 0
So 102402-46-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H14NO5P/c8-7(14(11,12)13)4-2-1-3-5(7)6(9)10/h5H,1-4,8H2,(H,9,10)(H2,11,12,13)
102402-46-0Relevant articles and documents
Amidoalkylation of phosphorus trichloride with acetamide and functionalized cyclic ketones-evidence of dominating role of side-reactions
Dziuganowska, Zofia A.,Andrasiak, Iga,lepokura, Katarzyna,Kafarski, Pawel
, p. 1068 - 1075 (2014/11/07)
The course of the reaction between phosphorus trichloride, acetamide and ethyl oxoalkanecarboxylates was studied in terms of the production of side-products. When ethyl 2-oxocycloalkane-and 4-oxocyclohexanecarboxylates were used as substrates, not only mi
Amidoalkylation of phosphorus trichloride with acetamide and alkyl oxocycloalkanecarboxylates
Ziora, Zyta,Kafarski, PaweL
experimental part, p. 1047 - 1053 (2009/12/03)
The course of the reaction between phosphorus trichloride, acetamide, and ethyl oxoalkanecarboxylates was studied in terms of the production of side-products. When alkyl 2-oxocycloalkanecarboxylates were used as substrates, together with the expected prod
