10241-97-1 Usage
Uses
Used in Pharmaceutical Industry:
5-METHYLINDOLE-2-CARBOXYLIC ACID is used as a reactant for the synthesis of Pin1 inhibitors, which are potential antitumor agents. Pin1 is an enzyme that plays a crucial role in cell proliferation and cancer development, and its inhibition can lead to the suppression of tumor growth.
5-METHYLINDOLE-2-CARBOXYLIC ACID is also used as a reactant in the preparation of non-imidazole human histamine H4 receptor antagonists. These antagonists have potential applications in the treatment of various conditions, such as allergies, inflammatory diseases, and asthma, by blocking the action of histamine, a molecule involved in immune responses and inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 10241-97-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,4 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10241-97:
(7*1)+(6*0)+(5*2)+(4*4)+(3*1)+(2*9)+(1*7)=61
61 % 10 = 1
So 10241-97-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H9NO2/c1-6-2-3-8-7(4-6)5-9(11-8)10(12)13/h2-5,11H,1H3,(H,12,13)
10241-97-1Relevant articles and documents
Novel 3,4-Dihydroquinolin-2(1H)-one inhibitors of human glycogen phosphorylase a
Rosauer, Keith G.,Ogawa, Anthony K.,Willoughby, Chris A.,Ellsworth, Kenneth P.,Geissler, Wayne M.,Myers, Robert W.,Deng, Qiaolin,Chapman, Kevin T.,Harris, Georgianna,Moller, David E.
, p. 4385 - 4388 (2007/10/03)
The preparation of a series of substituted indoles coupled to six- and seven-membered cyclic lactams is described and their role as human glycogen phosphorylase a inhibitors discussed. The SAR of the indole moiety and lactam ring are presented.
