102539-64-0Relevant articles and documents
Synthesis of benzofuran scaffold-based potential PTP-1B inhibitors
Dixit, Manish,Tripathi, Brajendra K.,Tamrakar, Akhilesh K.,Srivastava, Arvind K.,Kumar, Brijesh,Goel, Atul
, p. 727 - 734 (2007/10/03)
Protein tyrosine phosphatase 1B (PTP-1B) is an enzyme that plays a critical role in down-regulating insulin signaling through dephosphorylation of the insulin receptor. Studies have shown that PTP-1B knockout mice showed increased insulin sensitivity in m
A controlled synthesis of nature-mimicking benzofurans and their corresponding dimers
Dixit, Manish,Sharon, Ashoke,Maulik, Prakas R.,Goel, Atul
, p. 1497 - 1502 (2007/10/03)
Benzofurans functionalized with hydroxy and acetyl functionalities are not only the core structures found in a large number of biologically important natural products, but also the vital precursors for several naturally occurring furanoflavonoids. Numerou