10287-60-2Relevant articles and documents
An Improved method for synthesis of N-stearoyl and N-palmitoylethanolamine
Wang, Xiaosan,Wang, Tong,Wang, Xingguo
, p. 1305 - 1313 (2012)
Certain N-acylethanolamines interact with cannabinoid receptors and have anorexic and neuroprotective effects. Traditional methods for the synthesis of N-acylethanolamines use fatty acid chlorides, fatty acid methyl esters, free fatty acids and triacylgly
METHOD OF MAKING FATTY ACID N-ACYLALKANOLAMINES
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Paragraph 0069-0074; 0076-0082; 0089; 0090, (2013/11/19)
The present invention relates to methods for making a fatty acid N-acylalkanolamine having the formula: One of the methods comprises the steps of providing a vinyl ester of a fatty acid having the formula: providing a primary or secondary alkanolamine having the formula: NHR1R2; and reacting the vinyl ester of the fatty acid with the alkanolamine under conditions effective to form the fatty acid N-acylalkanolamine. The other method comprises the steps of providing a fatty acid; purifying the fatty acid; providing a primary or secondary alkanolamine having the formula: NHR1R2; reacting the fatty acid with the alkanolamine under conditions effective to form the fatty acid N-acylalkanolamine; and purifying the formed fatty acid N-acylalkanolamine.