102910-31-6

Basic information

• Product Name: PROPYL-D7 ALCOHOL
• Synonyms: 1-PROPANOL-1,1,2,2,3,3,3-D7;N-PROPANOL (D7);PROPANOL-D7;PROPYL-D7 ALCOHOL;PROPYL-D7 ALCOHOL 98%;1-propan-d7-ol;1-Propan-d7-ol, Propyl-d7 alcohol;n-Propyl-d7 Alcohol
• CAS NO: 102910-31-6
• Molecular Formula: C₃H₈O
• Molecular Weight: 67.14
• EINECS: 200-746-9
• Mol File: 102910-31-6.mol

Chemical Properties

• Melting Point: -127 °C(lit.)
• Boiling Point: 97 °C(lit.)
• Appearance: /
• Density: 0.896 g/mL at 25 °C
• CAS DataBase Reference: PROPYL-D7 ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: PROPYL-D7 ALCOHOL(102910-31-6)
• EPA Substance Registry System: PROPYL-D7 ALCOHOL(102910-31-6)

Safety Data

• Hazard Codes: F,Xi
• Statements: 11-41-67
• Safety Statements: 7-16-24-26-39
• Hazardous Substances Data: 102910-31-6(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research:
PROPYL-D7 ALCOHOL is used as a tracer compound for tracking the movement and transformation of molecules in chemical reactions. Its deuterated nature allows researchers to distinguish it from other compounds and monitor its behavior under various conditions.
Used in Industrial Applications:
PROPYL-D7 ALCOHOL is used as a deuterated solvent in industrial processes where the tracking of specific chemical reactions is required. Its unique properties enable the monitoring of reaction pathways and the optimization of process efficiency.
Used in Analytical Chemistry:
PROPYL-D7 ALCOHOL is used as an internal standard in analytical chemistry for accurate quantification of target compounds. The presence of deuterium atoms provides a distinct signature, facilitating precise measurements and enhancing the reliability of analytical results.
Used in Pharmaceutical Development:
PROPYL-D7 ALCOHOL is used as a deuterated analog in the synthesis of pharmaceutical compounds. Its incorporation can provide insights into the metabolic pathways and pharmacokinetics of drug candidates, aiding in the optimization of drug design and development.
Used in Material Science:
PROPYL-D7 ALCOHOL is used in the study of material properties and behavior under various conditions. Its deuterated nature allows for the investigation of molecular dynamics and interactions in materials, contributing to the advancement of material science research.

Upstream product

• 1265919-32-1 d5-ethyl propionate 
• 60153-92-6 propionic acid-d5 
• 3634-35-3 Propiolsaeure 

Downstream Products

• 59012-23-6 (1-2H₂,2-2H₂,3-2H₃)-iodopropane 

Relevant articles and documents

Inherent asymmetry of constitutionally equivalent methyl groups in the H/D equilibration of n- and i-C3H7Fe(OH)+ complexes

Transiently formed, constitutionally identical methyl groups remain inequivalent in the course of an n-propyl?isopropyl isomerization (see scheme) operative in Fe÷-mediated dehydration of propanols. The reversibility of the β-hydrogen transfer steps is addressed by examination of the H/D equilibration in metastable complexes of Fe+ with a set of selectivity deuterated propanols by using tandem mass spectrometry.

Intramolecular Thermal Motions in Liquid n-Propanol (+ Glycerol), A Proton Magnetic Relaxation Study. 2

The proton magnetic relaxation times T1 and T2 of the four n-propanol species HOC3D7, DOCH2CD2CD3, DOCD2CH2CD3, and DOCD2CD2CH3 have been measured at the resonance frequency ν = 12 MHz as a function of the temperature in the range 80 1 measurements were performed at a second frequency, ν = 48 MHz, as well.Further measurements of the same general kind were done on the mixtures n-propanol + 50 mol percent glycerol (glycerol-d5 and -d8) and n-propanol + 70 mol percent glycerol (glycerol-d5 and -d8).Isotopic dilution measurements with constant content of propanol and varying degree of deuteration were made to obtain the intramolecular relaxation rates.The proton NMR spectra of the four propanol species were recorded at T = 130 K.From all these data correlation times for the various proton-proton vectors were derived.It turned out that to each motion a slow and a fast mode contribution exists, however, the results are not compatible with the model of a molecule as a system of rigid bodies connected by axes about which rotation occurs.A formal description and interpretation is given involving the molecule concept without the presupposition of a microscopic rigid body.

CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR

The present invention relates to new cyclopropyl modulators of P2Y12 receptor activity, pharmaceutical compositions thereof, and methods of use thereof.

Anwendung der Perdeuteroallyl Schutz-Gruppe

Facile and straightforward transformations of propynoic acid into perdeuterated allyl bromide are described.The advantage of a pentadeuteroallyl protection for the 1H-N.M.R. structure elucidation of complex carbohydrate derivatives is demonstrated in the