102991-08-2

Basic information

• Product Name: Acetic acid, hydroxy-, (4-methoxyphenyl)methyl ester
• CAS NO: 102991-08-2
• Molecular Formula: C10H12O4
• Molecular Weight: 196.203
• Mol File: 102991-08-2.mol

Chemical Properties

• CAS DataBase Reference: Acetic acid, hydroxy-, (4-methoxyphenyl)methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, hydroxy-, (4-methoxyphenyl)methyl ester(102991-08-2)
• EPA Substance Registry System: Acetic acid, hydroxy-, (4-methoxyphenyl)methyl ester(102991-08-2)

Safety Data

• Hazardous Substances Data: 102991-08-2(Hazardous Substances Data)

Upstream product

• 25289-18-3 sodium glycolate 
• 824-94-2 p-methoxybenzyl chloride 
• 79-14-1 glycolic Acid 

Downstream Products

• 452979-20-3 4-Methoxybenzyl {[(allyloxy)carbonyl]oxy}acetate 
• 1450727-79-3 C₃₀H₃₆N₄O₆ 
• 1450727-78-2 C₁₅H₁₅N₃O₅ 

Relevant articles and documents

AMIDE DERIVATIVE

Provided are a compound having an excellent hypoglycemic action, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause an increase in the blood sugar level due to abnormal sugar metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.

Synthesis, cleavage, and antifungal activity of a number of novel, water-soluble ester prodrugs of antifungal triazole CS-758

In this study, the synthesis and evaluation of a number of esters of CS-758 as injectable prodrugs are described. Phosphoryl ester 1a was soluble in water (>30 mg/mL) and was converted to CS-758 in human liver microsome. It was also converted to CS-758 in rats after iv administration, wherein the bioavailability of CS-758 was 53%. Compound 1a (iv) reduced the viable cell counts in kidneys in a murine systemic Candida albicans infection model, wherein the effect was comparable to or slightly superior to that of CS-758 (po). The prodrug 1a proved to be a promising injectable antifungal agent whose further evaluation is warranted.

WATER-SOLUBLE TRIAZOLE FUNGICIDE

A triazole compound of the general formula (I) or a pharmacologically acceptable salt thereof: [wherein,X represents a group of formula X-OH which has antifungal activity,L represents a -(adjacently substituted C6-C10 aryl)-CH2-group and the like, andR represents a -P(=O) (OH)2 group and the like.