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103151-40-2

4-amino-2-(4-methyl-1-piperazinyl)-5-pyrimidinecarbonitrile is a pyrimidinecarbonitrile derivative with the molecular formula C10H14N6. It is a member of the pyrimidine class of compounds, characterized by a pyrimidine ring with an amino group at the 4-position, a piperazine ring at the 2-position, and a carbonitrile group at the 5-position. This chemical compound is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and has potential applications in the development of new therapeutic agents, gaining importance in medicinal chemistry research.

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  • 103151-40-2 Structure

  • Basic information

    1. Product Name: 4-amino-2-(4-methyl-1-piperazinyl)-5-pyrimidinecarbonitrile
    2. Synonyms: 4-amino-2-(4-methyl-1-piperazinyl)-5-pyrimidinecarbonitrile;4-amino-2-(4-methylpiperazin-1-yl)pyrimidine-5-carbonitrile
    3. CAS NO:103151-40-2
    4. Molecular Formula: C10H14N6
    5. Molecular Weight: 218.263
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 103151-40-2.mol

  • Chemical Properties

    1. Melting Point: 189℃
    2. Boiling Point: 457.4 °C at 760 mmHg
    3. Flash Point: 230.5 °C
    4. Appearance: /
    5. Density: 1.31
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-amino-2-(4-methyl-1-piperazinyl)-5-pyrimidinecarbonitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-amino-2-(4-methyl-1-piperazinyl)-5-pyrimidinecarbonitrile(103151-40-2)
    11. EPA Substance Registry System: 4-amino-2-(4-methyl-1-piperazinyl)-5-pyrimidinecarbonitrile(103151-40-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 103151-40-2(Hazardous Substances Data)

103151-40-2 Usage

Uses

Used in Pharmaceutical Industry:
4-amino-2-(4-methyl-1-piperazinyl)-5-pyrimidinecarbonitrile is used as a building block for the synthesis of various drugs due to its unique chemical structure and potential in medicinal chemistry research.
Used in Drug Development:
4-amino-2-(4-methyl-1-piperazinyl)-5-pyrimidinecarbonitrile is used as a key intermediate in the development of new therapeutic agents, contributing to the discovery and synthesis of novel pharmaceutical compounds with potential applications in treating various diseases and medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 103151-40-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,1,5 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 103151-40:
(8*1)+(7*0)+(6*3)+(5*1)+(4*5)+(3*1)+(2*4)+(1*0)=62
62 % 10 = 2
So 103151-40-2 is a valid CAS Registry Number.

103151-40-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-amino-2-(4-methylpiperazin-1-yl)pyrimidine-5-carbonitrile

1.2 Other means of identification

Product number -
Other names 4-Amino-2-(N'-methyl-piperazino)-5-cyan-pyrimidin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103151-40-2 SDS

103151-40-2Relevant articles and documents

Facile synthesis of pyrazolo[3,4-d]pyrimidines and pyrimido[4,5-d] pyrimidin-4-one derivatives

Katiyar, Sanjay Babu,Kumar, Arun,Chauhan, Prem M. S.

, p. 2963 - 2973 (2007/10/03)

Pyrazolopyrimidine and pyrimidopyrimidine derivatives have shown a wide range of biological activities such as acting as A1 adenosine receptors, kinase insert domain receptor (KDR), Rous sarcoma oncogene (Src), epidermal growth factor receptor (EGFR), antiproliferative, dihydrofolate reductase (DHFR), antimicrobial, antifungal, and lipid peroxidation. Because of this wide range of activities, we have synthesized pyrazolo[3,4-d]pyrimidines and pyrimido[4,5-d]pyrimidin-4-one derivatives. Copyright Taylor & Francis Group, LLC.

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