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2-Methyl-2,3-dihydro-benzofuran-5-carboxylic acid is a carboxylic acid derivative of benzofuran, a heterocyclic organic compound with the molecular formula C11H10O3. It is a white to off-white crystalline powder with a melting point of approximately 157-160°C. This chemical is utilized in pharmaceutical and research applications and has been investigated for its potential biological and pharmacological properties.

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  • 103204-80-4 Structure
  • Basic information

    1. Product Name: 2-METHYL-2,3-DIHYDRO-BENZOFURAN-5-CARBOXYLIC ACID
    2. Synonyms: TIMTEC-BB SBB010622;2-METHYL-2,3-DIHYDRO-BENZOFURAN-5-CARBOXYLIC ACID;2-methyl-2,3-dihydro-1-benzofuran-5-carboxylic acid
    3. CAS NO:103204-80-4
    4. Molecular Formula: C10H10O3
    5. Molecular Weight: 178.18
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 103204-80-4.mol
  • Chemical Properties

    1. Melting Point: 149-150 °C
    2. Boiling Point: 333.1 ºC at 760 mmHg
    3. Flash Point: 136.2 ºC
    4. Appearance: /
    5. Density: 1.254 g/cm3
    6. Vapor Pressure: 5.54E-05mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 4.55±0.40(Predicted)
    11. CAS DataBase Reference: 2-METHYL-2,3-DIHYDRO-BENZOFURAN-5-CARBOXYLIC ACID(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-METHYL-2,3-DIHYDRO-BENZOFURAN-5-CARBOXYLIC ACID(103204-80-4)
    13. EPA Substance Registry System: 2-METHYL-2,3-DIHYDRO-BENZOFURAN-5-CARBOXYLIC ACID(103204-80-4)
  • Safety Data

    1. Hazard Codes: Xi,Xn
    2. Statements: 22
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 103204-80-4(Hazardous Substances Data)

103204-80-4 Usage

Uses

Used in Pharmaceutical Applications:
2-Methyl-2,3-dihydro-benzofuran-5-carboxylic acid is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure and properties make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Research Applications:
In the field of research, 2-Methyl-2,3-dihydro-benzofuran-5-carboxylic acid is used as a chemical probe to study the biological and pharmacological properties of benzofuran derivatives. It aids in understanding the structure-activity relationships and potential therapeutic effects of these compounds.
Used in Chemical Synthesis:
2-Methyl-2,3-dihydro-benzofuran-5-carboxylic acid is used as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its carboxylic acid functionality allows for further chemical modifications and the formation of diverse chemical entities.
It is important to handle 2-Methyl-2,3-dihydro-benzofuran-5-carboxylic acid with care, as it may have hazardous effects if mishandled or improperly used. Proper safety measures and precautions should be taken during its synthesis, storage, and application to minimize potential risks.

Check Digit Verification of cas no

The CAS Registry Mumber 103204-80-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,2,0 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 103204-80:
(8*1)+(7*0)+(6*3)+(5*2)+(4*0)+(3*4)+(2*8)+(1*0)=64
64 % 10 = 4
So 103204-80-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H10O3/c1-6-4-8-5-7(10(11)12)2-3-9(8)13-6/h2-3,5-6H,4H2,1H3,(H,11,12)/p-1/t6-/m0/s1

103204-80-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-methyl-2,3-dihydro-1-benzofuran-5-carboxylic acid

1.2 Other means of identification

Product number -
Other names 2-Methyl-2,3-dihydro-benzofuran-5-carbonsaeure

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103204-80-4 SDS

103204-80-4Downstream Products

103204-80-4Relevant articles and documents

Zirconium(IV) chloride catalyzed cyclization of ortho-allylphenols: Synthesis of 2-methyl-2,3-dihydrobenzofurans

Meshram,Premalatha,Rameshbabu,Eeshwaraiah,Yadav

, p. 3091 - 3097 (2004)

Intramolecular cyclization of ortho-allylphenols has been carried out using zirconium (IV) chloride in mild condition. This method avoids the use of expensive reagents and leads to highly functionalized dihydrobenzofurans.

INHIBITORS OF LYSINE METHYL TRANSFERASE

-

, (2015/06/08)

There are disclosed compounds that are inhibitors of EZH2, pharmaceutical compositions containing said compounds and methods of treating hyperproliferative, inflammatory, infectious, and immunoregulatory disorders and diseases utilizing the compounds of t

Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method

-

, (2008/06/13)

A mesomorphic compound of the formula (I) having a coumaran skeleton is suitable as a component for a liquid crystal composition providing improved response characteristics. A liquid crystal device is constituted by disposing the liquid crystal composition between a pair of electrode plates. The liquid crystal device is used as a display panel constituting a display apparatus providing good display characteristics.

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