1034330-85-2

Basic information

• Product Name: 4'-chloro-3-(1H-tetrazol-5-yl)-biphenyl-4-ylamine
• Synonyms: 4'-chloro-3-(1H-tetrazol-5-yl)-biphenyl-4-ylamine
• CAS NO: 1034330-85-2
• Molecular Weight: 271.709
• Mol File: 1034330-85-2.mol

Chemical Properties

• CAS DataBase Reference: 4'-chloro-3-(1H-tetrazol-5-yl)-biphenyl-4-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-chloro-3-(1H-tetrazol-5-yl)-biphenyl-4-ylamine(1034330-85-2)
• EPA Substance Registry System: 4'-chloro-3-(1H-tetrazol-5-yl)-biphenyl-4-ylamine(1034330-85-2)

Safety Data

• Hazardous Substances Data: 1034330-85-2(Hazardous Substances Data)

Upstream product

• 39263-32-6 2-amino-5-bromobenzonitrile 
• 1679-18-1 4-Chlorophenylboronic acid 
• 1034330-83-0 4-amino-4'-chloro-biphenyl-3-carbonitrile 

Downstream Products

• 1034331-25-3 (E)-3-(3,5-bis-trifluoromethyl-phenyl)-N-[4'-chloro-3-(1H-tetrazol-5-yl)-biphenyl-4-yl]-acrylamide 
• 1080450-86-7 2-(4-chloro-phenyl)-N-[4'-chloro-3-(1H-tetrazol-5-yl)-biphenyl-4-yl]-acetamide 

Relevant articles and documents

NOVEL BENZAMIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS

This invention relates to novel benzamidine derivatives of formula (I) that are found to be potent modulators of potassium channels and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels. A stereoisomer or a mixture of its stereoisomers, or an N-oxide thereof, or a pharmaceutically-acceptable addition salt thereof, wherein B may be absent (i.e. no heterocyclic ring is formed); and when absent, the nitrogen next to B holds a hydrogen (i.e. "NH"), and A represents NH2 or OH; or B may be present (i.e. forms part of a heterocyclic ring); and when present, B represents C=O or C=S; and A represents NH or O; and wherein the rest of variables are as specified in claim 1.

ACETAMIDE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS

This invention relates to novel acetamide derivatives that are found to be potent modulators of ion channels, in particular potassium channels and chloride channels, and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels.

BETA-KETO-AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS

This invention relates to novel β-keto-amide derivatives that are found to be potent modulators of ion channels, and in particular potassium channels and chloride channels, and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels.

NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS

This invention relates to novel cinnamic amide derivatives that are found to be potent modulators of ion channels and, as such, they are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to modulation

DIPHENYLUREA DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS

The present invention relates to the medical use of a certain group of diphenyl urea derivatives as potassium channel blockers for treating cardiovascular diseases, an obstructive or inflammatory airway disease, urinary incontinence, psychosis, epilepsy o

DIPHENYLUREA DERIVATIVES AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS

The present invention relates to novel diphenylurea derivatives useful as chloride channel blockers. In other aspects the invention relates to the use of these compounds in a method for therapy, and to pharmaceutical compositions comprising the compounds