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7,8-Dihydroisoquinolin-5(6H)-one, hydrochloride is a chemical compound belonging to the isoquinoline class, widely utilized in pharmaceutical research for the development of innovative drugs and medications. This hydrochloride salt form enhances the solubility and stability of the compound, making it an advantageous choice for pharmaceutical formulations. It has demonstrated potential therapeutic effects in a range of medical conditions, such as neurodegenerative diseases, psychiatric disorders, and cancer, positioning it as a promising and valuable compound in medicinal chemistry and drug development.

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  • 103441-65-2 Structure
  • Basic information

    1. Product Name: 7,8-dihydroisoquinolin-5(6H)-one, hydrochloride
    2. Synonyms: 7,8-dihydroisoquinolin-5(6H)-one, hydrochloride;5(6H)-Isoquinolinone, 7,8-dihydro-, hydrochloride;7,8-Dihydro-6H-isoquinolin-5-one hydrochloride;5,6,7,8-Tetrahydroisoquinolin-5-one Hydrochloride;7,8-DIHYDROISOQUINOLIN-5(6H)-ONE HCL
    3. CAS NO:103441-65-2
    4. Molecular Formula: C9H10ClNO
    5. Molecular Weight: 183.6348
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 103441-65-2.mol
  • Chemical Properties

    1. Melting Point: 235-236 °C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 7,8-dihydroisoquinolin-5(6H)-one, hydrochloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7,8-dihydroisoquinolin-5(6H)-one, hydrochloride(103441-65-2)
    11. EPA Substance Registry System: 7,8-dihydroisoquinolin-5(6H)-one, hydrochloride(103441-65-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 103441-65-2(Hazardous Substances Data)

103441-65-2 Usage

Uses

Used in Pharmaceutical Research and Development:
7,8-Dihydroisoquinolin-5(6H)-one, hydrochloride is used as a key compound in pharmaceutical research for its potential therapeutic effects in various medical conditions. It is particularly valued for its ability to improve solubility and stability, which are critical factors in the development of effective drug formulations.
Used in the Treatment of Neurodegenerative Diseases:
In the field of neurodegenerative diseases, 7,8-Dihydroisoquinolin-5(6H)-one, hydrochloride is used as a potential therapeutic agent for its neuroprotective properties, aiming to slow down or halt the progression of conditions such as Alzheimer's and Parkinson's disease.
Used in Psychiatric Disorder Treatment:
7,8-Dihydroisoquinolin-5(6H)-one, hydrochloride is employed as a candidate for the treatment of psychiatric disorders, leveraging its potential to modulate neurotransmitter systems and alleviate symptoms associated with mental health conditions.
Used in Oncology Research:
In oncology, 7,8-Dihydroisoquinolin-5(6H)-one, hydrochloride is used as a compound of interest in cancer research, exploring its potential to target and inhibit the growth of cancer cells, offering a new avenue for cancer treatment strategies.
Used in Drug Formulation Development:
7,8-Dihydroisoquinolin-5(6H)-one, hydrochloride is utilized in the development of drug formulations, taking advantage of its hydrochloride salt form to enhance the compound's solubility and stability, thereby improving the overall effectiveness and safety of the medication.

Check Digit Verification of cas no

The CAS Registry Mumber 103441-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,4,4 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 103441-65:
(8*1)+(7*0)+(6*3)+(5*4)+(4*4)+(3*1)+(2*6)+(1*5)=82
82 % 10 = 2
So 103441-65-2 is a valid CAS Registry Number.

103441-65-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 7,8-dihydro-6H-isoquinolin-5-one,hydrochloride

1.2 Other means of identification

Product number -
Other names 7,8-Dihydro-6H-isochinolin-5-on,Hydrochlorid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103441-65-2 SDS

103441-65-2Relevant articles and documents

TRICYCLIC INDOLES AND (4,5-DIHYDRO) INDOLES

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Page/Page column 75, (2008/12/06)

The present invention provides tricyclic indoles and (4,5-dihydro) indoles of the formula (I) or a pharmaceutically acceptable salt thereof: wherein the ring A represents a fused pyrazole, pyridine or pyrimidine, ----- means either simple or double carbon

CYCLOALKANOPYRIDINE DERIVATIVE

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, (2010/11/24)

Provided are cycloalkanopyridine derivatives of formula [I]: [wherein the symbols are the same as those stated in the description]. The compounds act as a nociceptin receptor antagonist, and are useful as medicines for diseases associated with a nociceptin receptor, for example, as a reliever against tolerance to a narcotic analgesic; a reliever against dependence on or addiction to a narcotic analgesic; an analgesic enhancer; an antiobesitic or appetite suppressor; a treating or prophylactic agent for cognitive impairment and dementia/amnesia; an agent for treating developmental cognitive abnormality; a remedy for schizophrenia; an agent for treating neurodegenerative diseases; an anti-depressant or treating agent for affective disorder; a treating or prophylactic agent for diabetes insipidus; a treating or prophylactic agent for polyuria; or a remedy for hypotension.

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