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6-aMino-3,4-dihydro-2H-chroMen-2-one is a heterocyclic chemical compound with the molecular formula C9H9NO2. It features a chromenone core and an amino group at the 6-position, which contributes to its potential pharmacological activity. 6-aMino-3,4-dihydro-2H-chroMen-2-one has been studied for its antioxidant, anti-inflammatory, and anti-cancer properties, making it a promising candidate for drug development. It also has potential applications in modulating cellular signaling pathways and gene expression.

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  • 103441-69-6 Structure
  • Basic information

    1. Product Name: 6-aMino-3,4-dihydro-2H-chroMen-2-one
    2. Synonyms: 6-aMino-2,3-dihydro-4H-chroMen-4-one;6-aMino-3,4-dihydro-2H-chroMen-2-one;6-AMinochroMan-4-one;6-AMinochroManone;6-AMINO-3,4-DIHYDRO-2H-1-BENZOPYRAN-4-ONE
    3. CAS NO:103441-69-6
    4. Molecular Formula: C9H9NO2
    5. Molecular Weight: 163.17326
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 103441-69-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 379.3±42.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.294±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 4.04±0.20(Predicted)
    10. CAS DataBase Reference: 6-aMino-3,4-dihydro-2H-chroMen-2-one(CAS DataBase Reference)
    11. NIST Chemistry Reference: 6-aMino-3,4-dihydro-2H-chroMen-2-one(103441-69-6)
    12. EPA Substance Registry System: 6-aMino-3,4-dihydro-2H-chroMen-2-one(103441-69-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 103441-69-6(Hazardous Substances Data)

103441-69-6 Usage

Uses

Used in Pharmaceutical Industry:
6-aMino-3,4-dihydro-2H-chroMen-2-one is used as a potential therapeutic agent for the treatment of various medical conditions due to its antioxidant, anti-inflammatory, and anti-cancer properties. Its ability to modulate cellular signaling pathways and gene expression makes it a valuable compound for drug development.
Used in Research Applications:
In the field of scientific research, 6-aMino-3,4-dihydro-2H-chroMen-2-one serves as a subject of study for understanding its pharmacological activity and potential use in treating different diseases. Its role in biological processes and interaction with cellular mechanisms is of interest to researchers working on drug discovery and development.

Check Digit Verification of cas no

The CAS Registry Mumber 103441-69-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,4,4 and 1 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 103441-69:
(8*1)+(7*0)+(6*3)+(5*4)+(4*4)+(3*1)+(2*6)+(1*9)=86
86 % 10 = 6
So 103441-69-6 is a valid CAS Registry Number.

103441-69-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-amino-2,3-dihydrochromen-4-one

1.2 Other means of identification

Product number -
Other names 4H-1-Benzopyran-4-one,6-amino-2,3-dihydro

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103441-69-6 SDS

103441-69-6Relevant articles and documents

Structurally-thrifty and visible-absorbing fluorophores

Chen, Yan,Li, Yanchun,Luo, Xiao,Qian, Xuhong,Sun, Zhenglong,Yang, Youjun,Zhu, Weihong

, (2021)

Fluorophores with a minimal push-pull backbone are actively pursued due to their potentials in biological labelling. Herein a series of structurally-thrifty and visible-absorbing fluorophores (SDXs) were successfully constructed following the D′D-π-A design strategy, in which a secondary donor (D′) was introduced in conjugation with the donor (D) to enhance its electron donating capability. For a very small scaffold, SDXs exhibit a surprisingly long-wavelength absorption band in the visible spectral range (λabs = 420 nm) and a strong green fluorescence emission (λem = 530 nm) with a fluorescence quantum yield up to 0.84. Notably, fluorescence of SDXs was quenched in hydrogen-bonding solvents, e.g. MeOH and H2O. This phenomenon renders SDXs feasibility for imaging of cellular non-hydrogen-bonding microenvironment, as demonstrated with BEAS-2B cells. These results proved that the D′D-π-A is a powerful design strategy to construct novel structurally-thrifty fluorophores.

ROR-GAMMA MODULATORS AND USES THEREOF

-

Page/Page column 48, (2016/01/21)

The present invention relates to a compound of formula I, or an isotopic form, stereoisomer, a tautomer, a pharmaceutically acceptable salt, a solvate, a polymorph, a prodrug, N-oxide or S-oxide thereof; and processes for their preparation. The invention further relates to pharmaceutical compositions containing the compounds and their use in the treatment of diseases or disorders mediated by RORγ.

Dihydrobenzopyran, thiochroman, tetrahydroquinoleine and tetrahydronaphthalene derivatives and their use in anti-cancer therapy

-

, (2012/08/28)

New dihydrobenzopyran, thiochroman, tetrahydroquinoleine and tetrahydronaphthalene derivatives and their use in anti-cancer therapy with the general formula :

DIHYDROBENZOPYRAN, THIOCHROMAN, TETRAHYDROQUINOLEINE AND TETRAHYDRONAPHTALENE DERIVATIVES AND THEIR USE IN ANTICANCER THERAPY

-

, (2012/08/28)

New dihydrobenzopyran, thiochroman, tetrahydroquinoleine and tetrahydronaphthalene derivatives and their use in anti-cancer therapy with the general formula (I).

SPIROAMINODIHYDROTHIAZINE DERIVATIVES

-

Page/Page column 65-66, (2010/04/03)

A compound represented by the general formula (I): or a pharmaceutically acceptable salt thereof, has an Aβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβ and typified by Alzheimer- type dementia.

PIPERIDINYLCHROMEN-6-YLSULFONAMIDE COMPOUNDS AS 5-HYDROXYTRYPTAMINE-6 LIGANDS

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Page/Page column 19, (2008/06/13)

The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of a CNS disorder relating to or affected by the 5-HT6 receptor.

Preparation of 6-substituted 4-chromanones

-

, (2008/06/13)

Disclosed is a practical and efficient process for preparing 6-substituted 4-chromanones from phenolic acrylate ester compounds derivable from para-substituted phenolic or thiophenolic compounds and beta-unsubstituted acrylic acid compounds which are esterifiable therewith. The process includes effecting rearrangement of a phenolic or thiophenolic acrylate ester in the presence of a rearrangement effective amount of hydrogen fluoride to the corresponding hydroxy - or mercapto (vinyl ketone) wherein the carbonyl carbon atom of the vinyl carboxy group is directly attached to the benzene ring ortho to the hydroxy or mercapto group. Thereafter, the vinyl ketone is cyclized to the corresponding 6-substituted 4-chromanone in the presence of a cyclization-effective amount of hydrogen fluoride. The 6-substituted 4-chromanones prepared by the process are useful as intermediates for preparing pharmaceutical agents.

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