1034912-40-7Relevant articles and documents
The discovery of AZD9164, a novel muscarinic M3 antagonist
Mete, Antonio,Bowers, Keith,Chevalier, Eric,Donald, David K.,Edwards, Helen,Escott, Katherine J.,Ford, Rhonan,Grime, Ken,Millichip, Ian,Teobald, Barry,Russell, Vince
scheme or table, p. 7440 - 7446 (2012/02/04)
The optimization of a new series of muscarinic M3 antagonists is described, leading to the identification of AZD9164 which was progressed into the clinic for evaluation of its potential as a treatment for COPD.
QUINUCLIDINOL DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS
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Page/Page column 34, (2010/05/13)
The invention provides compounds of formula (I) wherein R5 is a group of formula (II) or (III) and R1, R2, R3, R4, R6, a, b, Z, Y and X are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them, a process for preparing pharmaceutical compositions, their use in therapy and intermediates of use in their preparation.
PIPERIDINUM COMPOUNDS FOR THE TREATMENT OF OBSTRUCTIVE PULMONARY DISEASES (COPD)
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Page/Page column 55, (2008/12/06)
The invention provides compounds of formula (I), wherein R1, R2, R3, R4, R5, R6, g, h and X are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them, a process for preparing pharmaceutical compositions, their use in therapy and intermediates of use in their preparation.