103493-12-5Relevant articles and documents
Selective synthesis of carbamate protected polyamines using alkyl phenyl carbonates
Pittelkow, Michael,Lewinsky, Rasmus,Christensen, Jorn Bolstad
, p. 2195 - 2202 (2002)
Utilising alkyl phenyl carbonates, an economical, practical and versatile method for selective Boc, Cbz and Alloc protection of polyamines has been developed. This method allows Boc, Cbz and Alloc protection of primary amines in the presence of secondary amines by reaction of the polyamines with the alkyl phenyl carbonates. Also, this method allows mono carbamate protection of simple symmetrical aliphatic α,ω-alkanediamines in high yields with respect to the diamine. Finally, the method allows selective carbamate protection of a primary amine located on a primary carbon in the presence of a primary amine located on a secondary or a tertiary carbon in excellent yields.
Sinulamide: An H,K-ATPase inhibitor from a soft coral Sinularia sp.
Sata, Noriko U.,Sugano, Michihiro,Matsunaga, Shigeki,Fusetani, Nobuhiro
, p. 719 - 722 (2007/10/03)
Sinulamide (1), a new tetraprenylated spermine derivative, has been isolated from a soft coral Sinularia sp. as an H,K-ATPase inhibitor. The structure was assigned on the basis of spectroscopic data and confirmed by a total synthesis.
