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5-(1-Naphtyl)-3-phenylisoxazole is a complex organic compound with the molecular formula C20H13NO. It is characterized by a 5-membered isoxazole ring, which is fused to a 1-naphthyl group at the 5-position and a phenyl group at the 3-position. 5-(1-Naphtyl)-3-phenylisoxazole is known for its potential applications in the field of pharmaceuticals and materials science, particularly as a building block for the synthesis of more complex molecules. Its structure provides a rigid framework that can influence the properties of the molecules in which it is incorporated, making it a valuable component in the design of new drugs and other chemical products.

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  • 1035-93-4 Structure
  • Basic information

    1. Product Name: 5-(1-Naphtyl)-3-phenylisoxazole
    2. Synonyms: 5-(1-Naphtyl)-3-phenylisoxazole
    3. CAS NO:1035-93-4
    4. Molecular Formula: C19H13NO
    5. Molecular Weight: 0
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1035-93-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-(1-Naphtyl)-3-phenylisoxazole(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-(1-Naphtyl)-3-phenylisoxazole(1035-93-4)
    11. EPA Substance Registry System: 5-(1-Naphtyl)-3-phenylisoxazole(1035-93-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1035-93-4(Hazardous Substances Data)

1035-93-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1035-93-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,3 and 5 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1035-93:
(6*1)+(5*0)+(4*3)+(3*5)+(2*9)+(1*3)=54
54 % 10 = 4
So 1035-93-4 is a valid CAS Registry Number.

1035-93-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-(1′-naphthyl)-3-phenylisoxazole

1.2 Other means of identification

Product number -
Other names 5-Naphthalen-1-yl-3-phenyl-isoxazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1035-93-4 SDS

1035-93-4Downstream Products

1035-93-4Relevant articles and documents

Metal-Free Cyclopropanol Ring-Opening C(sp3)-C(sp2) Cross-Couplings with Aryl Sulfoxides

Chen, Dengfeng,Fu, Yuanyuan,Cao, Xiaoji,Luo, Jinyue,Wang, Fei,Huang, Shenlin

, p. 5600 - 5605 (2019/08/01)

A metal-free method for formal β-arylation/heteroarylation of ketones through efficient cyclopropanol ring-opening cross-couplings with aryl sulfoxides at room temperature has been developed. This protocol shows a broad substrate scope and promising scalability. In addition, the utility of the β-arylated ketones is further demonstrated through a variety of postcoupling transformations and synthetic applications.

TBAI-catalyzed intramolecular annulation of chalcone oximes toward isoxazoles

Abdukader, Ablimit,Sun, Yadong,Zhang, Zengpeng,Liu, Chenjiang

, p. 43 - 47 (2017/11/23)

A TBAI-catalyzed intramolecular annulation of chalcone oximes toward isoxazoles was developed, providing 3,5-diarylisoxazoles in good yields. Functional groups such as methoxy, ethyoxyl, chloro, bromo, fluoro and nitro were well tolerated in this reaction

Phosphine- and copper-free palladium catalyzed one-pot four-component carbonylation reaction for the synthesis of isoxazoles and pyrazoles

Iranpoor, Nasser,Firouzabadi, Habib,Etemadi-Davan, Elham

supporting information, p. 837 - 840 (2016/02/05)

The palladium catalyzed one-pot synthesis of isoxazoles and pyrazoles from aryl iodides, terminal alkynes, chromium hexacarbonyl and hydroxylamine hydrochloride or aqueous hydrazine solution is described. The Sonogashira carbonylative coupling intermediate was trapped in situ by hydroxylamine hydrochloride or aqueous hydrazine to deliver isoxazoles or pyrazoles, respectively, in high yields. This efficient method proceeds at atmospheric pressure and moderate temperature and does not require the use of copper, phosphine ligands or gaseous carbon monoxide.

Preparation of 3,5-disubstituted pyrazoles and isoxazoles from terminal alkynes, aldehydes, hydrazines, and hydroxylamine

Harigae, Ryo,Moriyama, Katsuhiko,Togo, Hideo

, p. 2049 - 2058 (2014/04/03)

The reaction of terminal alkynes with n-BuLi, and then with aldehydes, followed by the treatment with molecular iodine, and subsequently hydrazines or hydroxylamine provided the corresponding 3,5-disubstituted pyrazoles or isoxazoles in good yields with high regioselectivity, through the formations of propargyl secondary alkoxides and α-alkynyl ketones. The present reactions are one-pot preparation of 3,5-disubstituted pyrazoles from terminal alkynes, aldehydes, molecular iodine, and hydrazines, and 3,5-disubstituted isoxazoles from terminal alkynes, aldehydes, molecular iodine, and hydroxylamine.

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