- Small-scale screening of novel biobased monomers: the curious case of 1,3-cyclopentanediol
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In this work, we report on the small scale polycondensation and consecutive analysis of novel polyesters based on the potentially renewable 1,3-cyclopentanediol (CPdiol). To avoid evaporation of monomers during thin-film polymerization reactions, trimer pre-polyesters have been synthesized from the corresponding acid-chlorides with diol monomers. Polymerization of these trimers was explored by thermogravimetric analysis to identify potential side reactions, and to assess the ideal polymerization temperature. In general we observe that trans-1,3-cyclopentanediol exhibits good thermal stability up to 200 °C, whereas thermal dehydration of the alcohol end-groups occurs upon further heating. In contrast, for cis-1,3-cyclopentanediol, the ester bonds of the cyclopentane end-groups become labile, thereby generating carboxylic acid end-groups, and 3-cyclopentenol already at 180 °C. The thermal dehydration reactions yield double bond end-groups, which in turn facilitate cross-linking through cross-coupling and Diels-Alder reactions, leading to an increase in molecular weight. Despite the limited thermal stability of CPdiol, here we demonstrate that polymerization of CPdiol can successfully be achieved in thin-film polycondensation conditions at 180 °C, yielding molecular weights well above 10 kg mol?1.
- Noordzij,Dietz,Leoné,Wilsens,Rastogi
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- Solvent-dependent selective oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid under neat conditions
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An eco-friendly and economical route for the oxidation of 5-hydroxymethylfurfural (HMF) to 2,5-furandicarboxylic acid (FDCA) with atmospheric dioxygen as the sole oxidant under acid-, base-, metal-, and external initiator-free conditions in minimal solvent was reported. In the present reaction, the 1,2-diethoxyethylane has a dual role: reaction medium and free-radical initiator. The FDCA easily crystallizes during the reaction and was simple purified via recrystallization to provide the pure FDCA.
- Liu, Kai-Jian,Zeng, Tang-Yu,Zeng, Jia-Le,Gong, Shao-Feng,He, Jun-Yi,Lin, Ying-Wu,Tan, Jia-Xi,Cao, Zhong,He, Wei-Min
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- Novel diamidino-substituted derivatives of phenyl benzothiazolyl and dibenzothiazolyl furans and thiophenes: Synthesis, antiproliferative and DNA binding properties
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A series of new diamidino-, diisopropylamidino-, and diimidazolinyl- substituted derivatives of phenyl benzothiazolyl and dibenzothiazolyl furans and thiophenes were successfully prepared and evaluated for their antiproliferative activity on tumor cell lines in vitro, DNA binding propensity, and sequence selectivity as well as cellular distribution. A strong antiproliferative effect of the tested compounds was observed on all tested cell lines in a concentration-dependent response pattern. In general, imidazolinyl-substituted derivatives and/or the thiophene core were in correlation with increased antiproliferative activity. Two compounds (2b and 3b) were chosen for biological studies due to their differential antiproliferative properties. The DNA binding properties of this new series of compounds were assessed and evidenced their efficient minor groove binding properties with preferential interaction at AT-rich sites. Both compounds also present nuclear subcellular localization, suggesting that their cellular mode of action implies localization in the DNA compartment and direct inhibition of DNA replication and induction of apoptosis.
- Racané, Livio,Trali?-Kulenovi?, Vesna,Paveli?, Sandra Kraljevi?,Ratkaj, Ivana,Peixoto, Paul,Nhili, Raja,Depauw, Sabine,Hildebrand, Marie-Paule,David-Cordonnier, Marie-Hélène,Paveli?, Kre?imir,Karminski-Zamola, Grace
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- Pyridine/pyridinium symmetrical bisamides as functional materials: Aggregation, selective sensing and drug release
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Pyrrole and furan-based pyridine/pyridinium bisamides 1-4 have been designed and synthesized with a view to establishing new supramolecular gelators. The neutral gelators 1 and 2 were explored for cation binding. While the furan analogue 1 forms gel in the presence of Ag+ and Cu2+ ions in DMSO:H2O (1:1, v/v), the pyrrole conjugate 2 exhibits metallogel formation selectively with Ag+ ions and corroborates the role of the heteroatom in the spacer that modulates the self assembly behavior of the gelators. As an application, the 1-Cu gel selectively distinguishes thiol-based amino acids from a series of other amino acids as well as effectively discriminates d-glucose from its C2-epimer d-mannose by exhibiting gel to sol transformation. Additionally, encapsulation and subsequent release of the chemopreventive drug curcumin has been studied using the 1-Cu gel. Placement of a cholesterol unit onto the structures 1 and 2 resulted in charged structures 3 and 4 of which compound 4 produced an unambiguous visual readout of F- and AcO- ions by showing gel to sol transition.
- Panja, Santanu,Ghosh, Sumit,Ghosh, Kumaresh
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- Benzene-, pyrrole-, and furan-containing diametrically strapped calix[4]pyrroles - An experimental and theoretical study of hydrogen-bonding effects in chloride anion recognition
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(Figure Presented). Weak but important: The chloride anion binding properties of diametrically strapped calixpyrroles bearing benzene (see structure), pyrrole, and furan moieties in the strap have been studied in the solid state, in solution, and through theoretical analyses. The results obtained provide support for the notion that C-H...Cl- hydrogen bonds are significant and contribute substantially to the Cl- binding energetics.
- Yoon, Dae-Wi,Gross, Dustin E.,Lynch, Vincent M.,Sessler, Jonathan L.,Hay, Benjamin P.,Lee, Chang-Hee
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- A luminescent 2D zinc(II) metal–organic framework for selective sensing of Fe(III) ions and adsorption of organic dyes
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A 2D porous multifunctional Zn(II) metal–organic framework (MOF) [ZnL(H2O)3]·3H2O·DMF (BIPT-1·3H2O·DMF) has been successfully synthesized by using bis-(3-carboxy-phenyl)furan-2,5-dicarboxamide (H2L) a
- Chen, Fei,Cui, Xiu-Guo,Guo, Wen-Li,Hao, Xue-Min,Qu, Tao-Guang,Wang, Hao,Wu, Yi-Bo,Yang, Dan,Zhang, Min
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- Production of 5-(chloromethyl)furan-2-carbonyl chloride and furan-2,5-dicarbonyl chloride from biomass-derived 5-(chloromethyl)furfural (CMF)
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Acid chloride derivatives of 5-(chloromethyl)furan-2-carboxylic acid and furan-2,5-dicarboxylic acid (FDCA) can be produced in high yield by treatment of the precursor aldehydes 5-(chloromethyl) furfural (CMF) and 2,5-diformylfuran (DFF) with tert-butyl hypochlorite, which is inexpensively prepared from commercial bleach and tert-butanol. 5-(Chloromethyl)furan-2-carbonyl chloride (CMFCC) and furan-2,5-dicarbonyl chloride (FDCC) are highly useful intermediates for the production of furoate ester biofuels and polymers of FDCA.
- Dutta, Saikat,Wu, Linglin,Mascal, Mark
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- Renewable-based poly((ether)ester)s from 2,5-furandicarboxylic acid
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Polymers based on the renewable monomer 2,5-furandicarboxylic acid (FDCA) have witnessing an incessant growth in recent years, essentially motivated by their unique features and the current concerns about sustainability and environmental issues. However, to date, research has been mainly focused on FDCA-polyesters synthesis, while synthetic routes to afford poly((ether)ester)s remained unexplored until the present study, despite their inherent value. Herein, fully renewable-based poly((ether)ester)s from 2,5-furandicarboxylic acid, poly(ethylene glycol) (PEG) and isosorbide were straightforward synthesised by polycondensation reactions. Interestingly, these materials showed better or comparable thermal properties (e.g. glass transition temperature) than their fossil based counterparts, which can be simply tuned by changing the chain length of PEG segments and also by incorporating (or not) rigid isosorbide moieties. The ensuing products were characterised in detail by means of ATR FTIR, 1H NMR, TGA and DSC.
- Sousa, Andreia F.,Coelho, Jorge F.J.,Silvestre, Armando J.D.
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- Synthesis of fluorine-containing esters of 2,5-furandicarboxylic acid
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Fluorinated esters of 2,5-furandicarboxylic acid have been synthesized starting from 2,5-furan dicarboxylic acid dichloride and fluorine-containing diols. The reaction control was performed by means of 1H, 19F NMR, and IR-spectroscopy. Thermal stability, as well as glass transition temperature, and intrinsic viscosity parameters of the obtained oligomers have been determined.
- Sakharov,Smirnova,Glazkov,Yarosh
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- 2,5-Diamide-Substituted Five-Membered Heterocycles: Challenging Molecular Synthons
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We describe synthetic routes for preparing previously unknown 2,5-diamide-substituted five-membered heterocycles based on the thiophene, pyrrole, and furan ring systems by exploiting Curtius-like rearrangement reactions. Conformation analysis of the 2,5-diamidothiophene derivatives identified a "closed" conformation, in which the two carbonyl O atoms are in close contact with the thiophene S atom.
- Fabbro, Chiara,Armani, Simone,Carloni, Laure-Elie,De Leo, Federica,Wouters, Johan,Bonifazi, Davide
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- Selective recovery of rare earth elements using chelating ligands grafted on mesoporous surfaces
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Nowadays, rare earth elements (REEs) and their compounds are critical for the rapidly growing advanced technology sectors and clean energy demands. However, their separation and purification still remain challenging. Among different extracting agents used for REE separation, the diglycolamide (DGA)-based materials have attracted increasing attention as one of the most effective extracting agents. In this contribution, a series of new and element-selective sorbents were generated through derivatisation of the diglycolamide ligand (DGA), grafted to mesoporous silica and tested for the separation of rare earth elements. It is shown that, by tuning the ligand bite angle and its environment, it is possible to improve the selectivity towards specific rare earth elements.
- Florek, Justyna,Mushtaq, Ambreen,Larivière, Dominic,Cantin, Gabrielle,Fontaine, Frédéric-Georges,Kleitz, Freddy
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p. 103782 - 103789
(2015)
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- Poly(alkylene 2,5-furandicarboxylate)s (PEF and PBF) by ring opening polymerization
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The preparation of cyclic ethylene and butylene 2,5-furandicarboxylate oligoesters and their conversion to furan-based polyesters poly(ethylene furanoate) (PEF) and poly(butylene furanoate) (PBF) by ring-opening polymerization (ROP) are described. The cyclic oligoesters were obtained in high yields by both high dilution condensation and thermal cyclodepolymerization methods, and they consisted of mixtures of small size species. Cyclic dimer, trimer and tetramer oligoesters were isolated by semipreparative chromatography and found to be crystalline compounds melting within the 140-200°C range. ROP catalyzed by Sn(Oct)2 of both mixtures and individual species afforded PEF and PBF with weight-average molecular weights between 50,000 and 60,000 g mol-1. Polymerization rate was found to be higher for butylene than for ethylene cyclic oligofuranoates, and also to increase slightly as cycle size decreased. The thermal properties of PEF and PBF prepared by ROP were in full agreement with those reported for these polyesters obtained by melt polycondensation.
- Carlos Morales-Huerta, Juan,Martínez De Ilarduya, Antxon,Mu?oz-Guerra, Sebastián
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- Novel methylselenoesters induce programed cell death via entosis in pancreatic cancer cells
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Redox active selenium (Se) compounds have gained substantial attention in the last decade as potential cancer therapeutic agents. Several Se compounds have shown high selectivity and sensitivity against malignant cells. The cytotoxic effects are exerted by their biologically active metabolites, with methylselenol (CH3SeH) being one of the key executors. In search of novel CH3SeH precursors, we previously synthesized a series of methylselenoesters that were active (GI50 3SeH precursors induced entosis by cell detachment through downregulation of cell division control protein 42 homolog (CDC42) and its downstream effector β1-integrin (CD29). To our knowledge, this is the first time that Se compounds have been reported to induce this type of cell death and is of importance in the characterization of the anticancerogenic properties of these compounds.
- Khalkar, Prajakta,Díaz-Argelich, Nuria,Palop, Juan Antonio,Sanmartín, Carmen,Fernandes, Aristi P.
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- Synthesis and characterization of poly(2,5-furan dicarboxylate)s based on a variety of diols
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Novel polyesters from renewable resources based on 2,5-dicarboxylic acid and several diols were synthesized and characterized using different polycondensation techniques. The aliphatic diols were sufficiently volatile to allow the use of polytransesterifications, which gave high-molecular weight semicrystalline materials with good thermal stability. In particular, the polyester based on ethylene glycol displayed properties comparable with those of its aromatic counterpart, poly(ethylene terephthalate), namely, the most important industrial polyester. The use of isosorbide gave rise to amorphous polymers with very stiff chains and hence a high glass transition temperature and an enhanced thermal stability. The interfacial polycondensation between the acid dichloride and hydroquinone produced a semicrystalline material with features similar to those of entirely aromatic polyesters, characterized essentially by the absence of melting and poor solubility, both associated with their remarkable chain rigidity. The replacement of hydroquinone with the corresponding benzylic diol was sufficient to provide a more tractable polyester. This study provided ample evidence in favor of the exploitation of furan monomers as renewable alternatives to fossil-based aromatic homologs. Copyright
- Gomes, Monica,Gandini, Alessandro,Silvestre, Armando J. D.,Reis, Bruno
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- Method for one-step synthesis of 2, 5-furandicarbonyl chloride
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The invention discloses a method for one-step synthesis of 2, 5-furandicarbonyl chloride, and relates to the technical field of organic synthesis, and the 2, 5-furandicarbonyl chloride is prepared from a raw material 5-formyl furoic acid through a one-pot method under the action of a catalyst and an organic solvent. Because the 5-formyl furoic acid used in the method can be prepared by selective oxidation of biomass platform molecule 5-hydroxymethylfurfural, the invention provides a sustainable development way for preparing 2, 5-furan diformyl chloride from renewable resources; the reaction conditions are mild, the 2, 5-furan dicarbonyl chloride can be prepared at high yield through a one-pot method, and the raw material 5-formyl furoic acid is converted into the 2, 5-furan dicarbonyl chloride at high selectivity.
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Paragraph 0022-0023; 0030-0091
(2021/03/30)
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- Method for preparing 2, 5-furandicarbonyl chloride from 5-chloromethylfurfural
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The invention discloses a method for preparing 2, 5-furan diformyl chloride from 5-chloromethyl furfural, and relates to the technical field of organic synthesis, wherein the 2, 5-furan diformyl chloride can be obtained by one-step reaction of 5-chloromethyl furfural under the action of a catalyst, a cocatalyst and an organic solvent. The 5-chloromethylfurfural used in the invention is commercialized, and can be directly prepared into the 5-chloromethylfurfural by deep hydrolysis of biomass, so the invention provides a sustainable development approach for preparing the 2, 5-furandicarboxylic acid dichloride by using renewable resources; and a metal organic framework material catalyst and a cocatalyst are adopted to convert the 5-chloromethyl furfural into the 2, 5-furan diformyl chloride with high selectivity through one-step reaction, and the reaction condition is mild and the yield is high.
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Paragraph 0009; 0029-0106
(2021/04/10)
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- Method for preparing 2,5-furandicarbonyldichloride from furan-2,5-dicarbaldehyde
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The application discloses a method for preparing 2,5-furandicarbonyldichloride from furan-2,5-dicarbaldehyde. Specifically the method comprises the following steps: adding an organic solvent and trichloroisocyanuric acid at 15-80 DEG C, and converting furan-2,5-dicarbaldehyde to 2,5-furandicarbonyldichloride under the catalysis of 2,2,6,6-tetramethylpiperidinooxy by the one pot method. According to the method, the raw material source is wide, the product yield is high, the process route is simple, and thus the method has potential industrial application prospects.
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Paragraph 0032-0111
(2019/08/31)
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- How Does the Hydrogen Bonding Interaction Influence the Properties of Polybenzoxazine? An Experimental Study Combined with Computer Simulation
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The formation of intra- or intermolecular hydrogen bonding and their influences on polybenzoxazine's properties were investigated after the model benzoxazine monomers (o-AB-fbz, o-AF-fbz, o-AP-fbz, p-AB-fbz, p-AF-fbz, p-AP-fbz) were synthesized. Because of the different electron-donating abilities of bridging units (benzene, furan and pyridine) in isophthalic acid (IPA), 2,5-furandicarboxylic acid (2,5-FDCA) and 2,6-pyridinedicarboxylic acid (2,6-PDCA), the strength of intramolecular H-bonding involved with the oxygen atom in oxazine ring in o-AB-fbz, o-AF-fbz and o-AP-fbz followed the order of o-AB-fbz > o-AF-fbz > o-AP-fbz, and the strength of the overall H-bonding was arranged as follows: o-AB-fbz g), and the influence of H-bonding on Tg was revealed by in situ FT-IR analysis. Molecular dynamics (MD) simulation was also applied to investigate the properties of synthesized polybenzoxazines and similar results were obtained. Not only the formation of H-bonding but also their effects on both the curing behaviors of benzoxazine monomers and the thermal properties of cured resins were systematically investigated, which would help us understand polybenzoxazines more deeply and might be a guideline for improving their comprehensive properties only by manipulating the H-bonding.
- Shen, Xiaobin,Cao, Lijun,Liu, Yuan,Dai, Jinyue,Liu, Xiaoqing,Zhu, Jin,Du, Shiyu
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p. 4782 - 4799
(2018/07/23)
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- Lubricating compositions containing isoprene based components
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A lubricating composition comprising a base oil of lubricating viscosity and one or more lubricant additives, wherein the base oil comprises or consists of a base stock which comprises or consists of at least one isoprenoid compound comprising: (i) one or
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Page/Page column 31; 32
(2018/11/30)
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- Fine chemicals from a biomass-derived dicarboxylic acid: Chiral bisoxazolines and their application in enantioselective Diels-Alder reactions
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2,5-Furandicarboxylic acid (FDCA) is a feedstock chemical readily available from cellulosic biomass. Six chiral bisoxazolines varying in the steric size of the blocking group have been synthesized from FDCA in modest to good overall yields. The effectiven
- Selvakumar, Sermadurai,Fairweather, Alisa,Ugrinov, Angel,Sibi, Mukund P.
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p. 151 - 157
(2019/04/25)
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- Novel methylselenoesters as antiproliferative agents
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Selenium (Se) compounds are potential therapeutic agents in cancer. Importantly, the biological effects of Se compounds are exerted by their metabolites, with methylselenol (CH3SeH) being one of the key executors. In this study, we developed a new series of methylselenoesters with different scaffolds aiming to modulate the release of CH3SeH. The fifteen compounds follow Lipinski’s Rule of Five and with exception of compounds 1 and 14, present better drug-likeness values than the positive control methylseleninic acid. The compounds were evaluated to determine their radical scavenging activity. Compound 11 reduced both DPPH and ABTS radicals. The cytotoxicity of the compounds was evaluated in a panel of five cancer cell lines (prostate, colon and lung carcinoma, mammary adenocarcinoma and chronic myelogenous leukemia) and two non-malignant (lung and mammary epithelial) cell lines. Ten compounds had GI50 values below 10 μM at 72 h in four cancer cell lines. Compounds 5 and 15 were chosen for further characterization of their mechanism of action in the mammary adenocarcinoma cell line due to their similarity with methylseleninic acid. Both compounds induced G2/M arrest whereas cell death was partially executed by caspases. The reduction and metabolism were also investigated, and both compounds were shown to be substrates for redox active enzyme thioredoxin reductase.
- Díaz-Argelich, Nuria,Encío, Ignacio,Plano, Daniel,Fernandes, Aristi P.,Palop, Juan Antonio,Sanmartín, Carmen
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- PREPARATION OF ACID CHLORIDES FROM 5-(CHLOROMETHYL) FURFURAL
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Acid chloride derivatives of 5-(chloromethyl)furan-2-carboxylic acid and furan-2,5-dicarboxylic acid (FDCA) can be produced in high yield by treatment of the precursor aldehydes 5-(chloromethyl)furfural (CMF) and 2,5-diformylfuran (DFF) with tert-butyl hypochlorite, which is inexpensively prepared from commercial bleach and tert-butanol. 5-(Chloromethyl)furan-2-carbonyl chloride (CMFCC) and furan-2,5-dicarbonyl chloride (FDCC) are highly useful intermediates for the production of furoate ester biofuels and polymers of FDCA.
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Paragraph 0051
(2016/12/22)
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- Heptyl esters of furan dicarboxylic acid as softeners
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The invention relates to the use of heptyl esters of furan dicarboxylic acid as softeners.
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Page/Page column 14
(2016/06/13)
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- Light-colored or colorless 2, 5-furandicarboxylic acid diester and method for preparing same
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The invention discloses light-colored or colorless 2, 5-furandicarboxylic acid diester and a method for preparing the same. The method includes steps of 1), reactively synthesizing 2, 5-furan benzenedicarbonyl chloride by the aid of acylating chlorination reagents and 2, 5-furandicarboxylic acid; 2), carrying out reaction on the 2, 5-furan benzenedicarbonyl chloride synthesized in the step 1) and alcohol and reactively generating corresponding 2, 5-furandicarboxylic acid diester; 3), neutralizing and washing 2, 5-furandicarboxylic acid diester reaction liquid obtained at the step 2) so as to obtain the colorless or light-colored 2, 5-furandicarboxylic acid diester. The light-colored or colorless 2, 5-furandicarboxylic acid diester and the method have the advantages that the light-colored or colorless 2, 5-furandicarboxylic acid diester is low in reaction temperature and little in alcohol decomposition as compared with existing 2, 5-furandicarboxylic acid diester prepared from acid alcohol by means of direct esterification, and the 2, 5-furandicarboxylic acid diester has light-colored or colorless characteristics; the light-colored or colorless 2, 5-furandicarboxylic acid diester and the method have excellent industrial application prospects.
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Paragraph 0018
(2016/12/07)
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- METHODS AND COMPOUNDS FOR PRODUCING NYLON 6,6
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Alternating co-polymers of cyclic dicarboxylic acids and cyclic diamines may be used to produce nylon 6,6. Di-substituted furan compounds may be used as the raw material for producing furan-dicarboxylic acids and/or furan-diamines. The furan-dicarboxylic acids and furan-diamines may be copolymerized to produce polymer precursors for nylon 6,6. The polymer precursors may be hydrogenated and/or deoxygenated to produce nylon 6,6.
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- 2,5-FURAN DICARBOXYLATE DERIVATIVES, AND USE THEREOF AS PLASTICIZERS
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The invention relates to mixtures of isononyl furan-2,5-dicarboxylate of formula (I), methods for producing said mixtures of isononyl furan-2,5-dicarboxylate of formula (I), compositions containing mixtures of isononyl furan-2,5-dicarboxylate of formula (I), uses of the mixtures of isononyl furan-2,5-dicarboxylate of formula (I) as plasticizers, and uses of the aforementioned compositions containing isononyl furan-2,5-dicarboxylate of formula (I).
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Page/Page column 6
(2012/09/10)
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- Synthesis and Am/Eu extraction of novel TODGA derivatives
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Various ligands with structural modifications of the N,N,N',N'-tetraoctyl- 3-oxapentanediamide (TODGA) skeleton were synthesised in good yields. These modifications include (1) the increase in chain length from one carbon to two carbons between the central ether oxygen atom and the amide moieties, (2) the addition of substituents on the carbon between the central oxygen atom and the amide moieties on one and both sides of the central oxygen, (3) the replacement of the central oxygen by a (substituted) nitrogen atom and (4) synthesis of a rigidified glycolamide. The effect of the structural modifications on their extraction behaviours toward Am(III) and Eu(III) at various nitric acid concentrations was studied. In most of the cases, the extraction does not exceed that of TODGA in the entire acidity range of 0.001-4mol/l HNO3. The extraction behaviour of monomethyl-TODGA derivative 10a resembles that of TODGA at high nitric acid concentrations. However, at lower acidities, its D values are much lower, which is beneficial for possible back-extraction steps. The aza-tripodal ligands 18a,b show reverse extraction properties compared to TODGA as far as the pH influence is concerned: at pH 2, the DAm values are 49.9 and 3.1, the DEu values are 5.9 and 0.2, and the S Am/Eu values are 8 and 11, respectively.
- Iqbal, Mudassir,Huskens, Jurriaan,Verboom, Willem,Sypula, Michal,Modolo, Giuseppe
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experimental part
p. 827 - 837
(2011/12/02)
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- Cyclization of propargylic amides: Mild access to oxazole derivatives
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The substrate scope, the mechanistic aspects of the gold-catalyzed oxazole synthesis, and substrates with different aliphatic, aromatic, and functional groups in the side chain were investigated. Even molecules with several propargyl amide groups could easily be converted, delivering di- and trioxazoles with interesting optical properties. Furthermore, the scope of the gold(I)-catalyzed alkylidene synthesis was investigated. Further functionalizations of these isolable intermediates of the oxazole synthesis were developed and chelate ligands can be obtained. The use of Barluenga's reagent offers a new and mild access to the synthetically valuable iodoalkylideneoxazoles from propargylic amides, this reagent being superior to other sources of halogens.
- Weyrauch, Jan P.,Hashmi, A. Stephen K.,Schuster, Andreas,Hengst, Tobias,Schetter, Stefanie,Littmann, Anna,Rudolph, Matthias,Hamzic, Melissa,Visus, Jorge,Rominger, Frank,Frey, Wolfgang,Bats, Jan W.
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supporting information; experimental part
p. 956 - 963
(2010/06/12)
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- 16. Ionophore vom Typ der 3-Oxapentadiamide
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A series of lipophilic 3-oxapentane diamides were prepared and their selectivity in membranes was studied.N,N,N',N'-Tetracyclohexyl-3-oxapentane diamide forms 1:2- and 1:3-metal/ligand-complexes with Mg(2+) and Ca(2+) respectively and induces a selectivity in membranes for Ca(2+) over Mg(2+) by a factor of about 10E4.
- Pretsch, Erno,Ammann, Daniel,Osswald, Hans F.,Guggi, Marc,Simon, Wilhelm
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p. 191 - 196
(2007/10/02)
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