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  • 10389-73-8 Structure
  • Basic information

    1. Product Name: Clortermine
    2. Synonyms: 1-(2-Chlorophenyl)-2-methyl-2-propaneamine;2-Chloro-α,α-dimethylbenzeneethanamine;Chlortermine;o-Chlorophentermine;[2-(2-chlorophenyl)-1,1-dimethyl-ethyl]amine;1-(2-chlorophenyl)-2-methyl-propan-2-amine;1-(2-chlorophenyl)-2-methylpropan-2-amine
    3. CAS NO:10389-73-8
    4. Molecular Formula: C10H14ClN
    5. Molecular Weight: 183.67786
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 10389-73-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: bp16 116-118°
    3. Flash Point: 127°C
    4. Appearance: /
    5. Density: 1.074g/cm3
    6. Vapor Pressure: 0.016mmHg at 25°C
    7. Refractive Index: 1.537
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 9.60±0.25(Predicted)
    11. CAS DataBase Reference: Clortermine(CAS DataBase Reference)
    12. NIST Chemistry Reference: Clortermine(10389-73-8)
    13. EPA Substance Registry System: Clortermine(10389-73-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 10389-73-8(Hazardous Substances Data)

10389-73-8 Usage

Uses

Anorexic.

Therapeutic Function

Antiobesity

Check Digit Verification of cas no

The CAS Registry Mumber 10389-73-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,8 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 10389-73:
(7*1)+(6*0)+(5*3)+(4*8)+(3*9)+(2*7)+(1*3)=98
98 % 10 = 8
So 10389-73-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H14ClN/c1-10(2,12)7-8-5-3-4-6-9(8)11/h3-6H,7,12H2,1-2H3

10389-73-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chlorophenyl)-2-methylpropan-2-amine

1.2 Other means of identification

Product number -
Other names CLORTERMINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10389-73-8 SDS

10389-73-8Relevant articles and documents

Direct Access to Primary Amines from Alkenes by Selective Metal-Free Hydroamination

Du, Yi-Dan,Chen, Bi-Hong,Shu, Wei

supporting information, p. 9875 - 9880 (2021/03/29)

Direct and selective synthesis of primary amines from easily available precursors is attractive yet challenging. Herein, we report the rapid synthesis of primary amines from alkenes via metal-free regioselective hydroamination at room temperature. Ammonium carbonate was used as ammonia surrogate for the first time, allowing for efficient conversion of terminal and internal alkenes into linear, α-branched, and α-tertiary primary amines under mild conditions. This method provides a straightforward and powerful approach to a wide spectrum of advanced, highly functionalized primary amines which are of particular interest in pharmaceutical chemistry and other areas.

ONE STEP PROCESS FOR THE PREPARATION OF PHENYL ETHYL AMINE DERIVATIVES

-

Page/Page column 6-7, (2021/06/11)

The present invention relates to a novel process for the preparation of phenyl ethyl amine derivatives by reacting a phenyl ethyl hydroxy compound with hydrogen cyanide followed by in situ hydrolysis.

Novel synthesis method of 2-methyl-1-substituted phenyl-2-propylamine compounds

-

Paragraph 0021; 0027- 0037; 0046; 0052; 0053, (2019/05/08)

The invention discloses a novel synthesis method of 2-methyl-1-substituted phenyl-2-propylamine compounds, and belongs to the field of material synthesis. The method comprises steps as follows: substituted benzyl halide is taken as a raw material and subj

Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases

-

, (2008/06/13)

The present invention provides compounds, and pharmaceutical compositions containing those compounds, that are active at metabotropic glutamate receptors. The compounds are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.

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