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DIETHYL 2-[(2,4-DIMETHYLANILINO)METHYLENE]MALONATE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

104007-06-9

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104007-06-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 104007-06-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,0,0 and 7 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 104007-06:
(8*1)+(7*0)+(6*4)+(5*0)+(4*0)+(3*7)+(2*0)+(1*6)=59
59 % 10 = 9
So 104007-06-9 is a valid CAS Registry Number.

104007-06-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2,4-dimethyl-anilinomethylene)-malonic acid diethyl ester

1.2 Other means of identification

Product number -
Other names DIETHYL 2-[(2,4-DIMETHYLANILINO)METHYLENE]MALONATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:104007-06-9 SDS

104007-06-9Relevant articles and documents

Evaluation of 3-carboxy-4(1H)-quinolones as inhibitors of human protein kinase CK2

Golub, Andriy G.,Yakovenko, Olexander Ya.,Bdzhola, Volodymyr G.,Sapelkin, Vladislav M.,Zien, Piotr,Yarmoluk, Sergiy M.

, p. 6443 - 6450 (2007/10/03)

Due to the emerging role of protein kinase CK2 as a molecule that participates not only in the development of some cancers but also in viral infections and inflammatory failures, small organic inhibitors of CK2, besides application in scientific research, may have therapeutic significance. In this paper, we present a new class of CK2 inhibitors-3-carboxy-4(1H)-quinolones. This class of inhibitors has been selected via receptor-based virtual screening of the Otava compound library. It was revealed that the most active compounds, 5,6,8-trichloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (7) (IC 50 = 0.3 μM) and 4-oxo-1,4-dihydrobenzo[h]quinoline-3-carboxylic acid (9) (IC50 = 1 μM), are ATP competitive (Ki values are 0.06 and 0.28 μM, respectively). Evaluation of the inhibitors on seven protein kinases shows considerable selectivity toward CK2. According to theoretical calculations and experimental data, a structural model describing the key features of 3-carboxy-4(1H)-quinolones responsible for tight binding to CK2 active site has been developed.

Design, synthesis, and biological evaluation of novel 4-hydro-quinoline-3- carboxamide derivatives as an immunomodulator

He, Jun-Feng,Yun, Liu-Hong,Yang, Ri-Fang,Xiao, Zhi-Yong,Cheng, Jun-Ping,Zhou, Wen-Xia,Zhang, Yong-Xiang

, p. 2980 - 2985 (2007/10/03)

A series of novel quinoline-3-carboxamide derivatives were synthesized and evaluated for their immunomodulatory activity. The compounds were tested in vitro for effects on spleen lymphocyte proliferation and TNF-α production by macrophage. Three compounds showed immunomodulatory profiles similar to and more potent than those of linomide and FR137316 and were selected for further pharmacological studies in vivo.

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