104149-14-6

Basic information

• Product Name: Bromofosfamide
• Synonyms: Bromofosfamide
• CAS NO: 104149-14-6
• Molecular Formula: C7H15BrClN2O2P
• Molecular Weight: 305.539
• Mol File: 104149-14-6.mol

Chemical Properties

• Boiling Point: 349.7°Cat760mmHg
• Flash Point: 165.3°C
• Appearance: /
• Density: 1.54g/cm³
• Vapor Pressure: 4.62E-05mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: Bromofosfamide(CAS DataBase Reference)
• NIST Chemistry Reference: Bromofosfamide(104149-14-6)
• EPA Substance Registry System: Bromofosfamide(104149-14-6)

Safety Data

• Hazardous Substances Data: 104149-14-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H15BrClN2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)

Upstream product

• 3778-73-2 ilfosfamide 
• 29102-47-4 2-aziridino-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide 

Relevant articles and documents

Synthesis and Antitumor Activity of Analogues of Ifosfamide Modified in the N-(2-Chloroethyl) Group

A series of 3-(2-chloroethyl)-N-(2-X-ethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxides with various X substituents have been prepared by cyclization of racemic ifosfamide or its enantiomers with sodium hydride and subsequent treatment of intermed

Process for the production of 2-(2-halogenoethylamino)-2-oxo-3-(2-halogenoethyl)-1.3.2.-oxazaphosphorinanes

Process for production of racemic or enantiomeric form of 2-(2-halogenoethylamino)-2-oxo-3-(2-halogenoethyl)-1.3.2.-oxazaphosphorinanes of general formula 1, STR1 wherein X and Y are the same or different and represent halogen atoms is based, according to invention, on the reaction of enantiomeric or racemic form of ethyleneimide of general formula 2, STR2 wherein Y is the same as above, with aqueous solution of hydrogen halide. Compounds of general formula 1, where X and Y are different and represent halogen atoms, possess better antileukemic activity than ifosfamide.