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3-Chloro-4-(pyridin-2-yl)aniline, an organic compound with the chemical formula C11H8ClN3, is a chlorinated aniline derivative featuring a pyridine ring attached to the fourth position of the aniline moiety. It serves as a crucial building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries, and is also utilized as an intermediate in the production of dyes and pigments. Due to its hazardous nature, it requires careful handling and storage.

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  • 1044209-44-0 Structure
  • Basic information

    1. Product Name: 3-CHLORO-4-(PYRIDIN-2-YL)ANILINE
    2. Synonyms: 3-CHLORO-4-(PYRIDIN-2-YL)ANILINE;3-chloro-4-(2-pyridinyl)Benzenamine
    3. CAS NO:1044209-44-0
    4. Molecular Formula: C11H9ClN2
    5. Molecular Weight: 204.65556
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1044209-44-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-CHLORO-4-(PYRIDIN-2-YL)ANILINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-CHLORO-4-(PYRIDIN-2-YL)ANILINE(1044209-44-0)
    11. EPA Substance Registry System: 3-CHLORO-4-(PYRIDIN-2-YL)ANILINE(1044209-44-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1044209-44-0(Hazardous Substances Data)

1044209-44-0 Usage

Uses

Used in Pharmaceutical Industry:
3-Chloro-4-(pyridin-2-yl)aniline is used as a precursor in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows for the creation of diverse compounds with potential medicinal properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3-chloro-4-(pyridin-2-yl)aniline is employed as a precursor for the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness in controlling pests and weeds, thereby improving crop yields and quality.
Used in Dyes and Pigments Production:
3-Chloro-4-(pyridin-2-yl)aniline is utilized as an intermediate in the production of dyes and pigments, imparting color to various materials and products. Its chemical properties enable the creation of stable and vibrant colorants for use in industries such as textiles, plastics, and paints.
Safety Precautions:
Given its hazardous nature, 3-chloro-4-(pyridin-2-yl)aniline should be handled and stored with caution. Proper safety measures, including the use of personal protective equipment and adherence to safety guidelines, are essential to minimize risks associated with its use.

Check Digit Verification of cas no

The CAS Registry Mumber 1044209-44-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,4,2,0 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1044209-44:
(9*1)+(8*0)+(7*4)+(6*4)+(5*2)+(4*0)+(3*9)+(2*4)+(1*4)=110
110 % 10 = 0
So 1044209-44-0 is a valid CAS Registry Number.

1044209-44-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-chloro-4-pyridin-2-ylaniline

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1044209-44-0 SDS

1044209-44-0Downstream Products

1044209-44-0Relevant articles and documents

Divergent Late-Stage (Hetero)aryl C?H Amination by the Pyridinium Radical Cation

Ham, Won Seok,Hillenbrand, Julius,Jacq, Jér?me,Genicot, Christophe,Ritter, Tobias

supporting information, p. 532 - 536 (2019/01/04)

(Hetero)arylamines constitute some of the most prevalent functional molecules, especially as pharmaceuticals. However, structurally complex aromatics currently cannot be converted into arylamines, so instead, each product isomer must be assembled through a multistep synthesis from simpler building blocks. Herein, we describe a late-stage aryl C?H amination reaction for the synthesis of complex primary arylamines that other reactions cannot access directly. We show and rationalize through a mechanistic analysis the reasons for the wide substrate scope and the constitutional diversity of the reaction, which gives access to molecules that would not have been readily available otherwise.

Theramutein modulators

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Page/Page column 176, (2010/02/17)

This invention relates to agents that are inhibitors or activators of variant forms of endogenous proteins and novel methods of identifying such variants. Of particular interest are inhibitors and activators of endogenous protein variants, encoded by genes which have mutated, which variants often arise or are at least first identified as having arisen following exposure to a chemical agent which is known to be an inhibitor or activator of the corresponding unmutated endogenous protein.

THERAMUTEIN MODULATORS

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Page/Page column 209-210, (2008/12/07)

This invention relates to agents that are inhibitors or activators of variant forms of endogenous proteins and novel methods of identifying such variants. Of particular interest are inhibitors and activators of endogenous protein variants, encoded by genes which have mutated, which variants often arise or are at least first identified as having arisen following exposure to a chemical agent which is known to be an inhibitor or activator of the corresponding unmutated endogenous protein.

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