Synthesis of DNP-modified GM3-based anticancer vaccine and evaluation of its immunological activities for cancer immunotherapy
Tumor-associated carbohydrate antigens (TACAs) are attractive targets for vaccine development. In this context, we described a strategy combining artificial TACA and glycoengineering for cancer vaccine development. A 2,4-ditrophenyl (DNP)-modified GM3 int
The invention described relates to 2,4-dinitrophenyl (DNP) labelling of nucleic acids or nucleic acid probes. Specifically, there is described compounds of formula I. A compound of formula I: X-Q-R*-NH-DNPwherein DNP is a 2,4-dinitrophenyl group; R* is a
-
(2008/06/13)
Pharmacokinetic studies with 3H-labelled synthetic antifibrinolytics
In rabbits and rats pharmacokinetic studies on the anti-fibrinolytics 4-aminomethylbenzoic acid (PAMBA), trans-4-aminomethylcyclohexane-1-carboxylic acid (AMCA), and epsilon-aminocaproic acid (EACA) were carried out using the tritium labelled compounds. F
Richter,Markwardt,Kloecking
p. 851 - 853
(2007/10/02)
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