1048990-21-1 Usage
Uses
Used in Organic Synthesis:
3'-Bromo-3-biphenylboronic acid is utilized as a building block in organic synthesis for the construction of a diverse range of organic molecules. Its ability to form stable intermediates and participate in various reactions makes it a versatile component in creating complex organic structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3'-Bromo-3-biphenylboronic acid is used as a reagent in the development of new drugs. Its unique chemical properties allow it to be incorporated into the molecular structures of potential therapeutic agents, contributing to the discovery of novel pharmaceutical compounds.
Used in Material Science:
3'-Bromo-3-biphenylboronic acid also finds applications in material science, where its structural and chemical characteristics are leveraged to develop new materials with specific properties. These materials can be used in various high-tech applications, including electronics, optoelectronics, and advanced materials for energy storage or conversion.
Used in Suzuki-Miyaura Cross-Coupling Reactions:
3'-Bromo-3-biphenylboronic acid is employed as a reagent in Suzuki-Miyaura cross-coupling reactions, a widely used method for forming carbon-carbon bonds. This reaction is crucial in the synthesis of various organic compounds, including those with potential applications in pharmaceuticals, agrochemicals, and materials science. The use of 3'-Bromo-3-biphenylboronic acid in these reactions enhances the efficiency and selectivity of the process, leading to the formation of desired products with fewer side reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 1048990-21-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,8,9,9 and 0 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1048990-21:
(9*1)+(8*0)+(7*4)+(6*8)+(5*9)+(4*9)+(3*0)+(2*2)+(1*1)=171
171 % 10 = 1
So 1048990-21-1 is a valid CAS Registry Number.
1048990-21-1Relevant articles and documents
A general and highly selective chelate-controlled intermolecular oxidative heck reaction
Delcamp, Jared H.,Brucks, Alexandria P.,White, M. Christina
supporting information; scheme or table, p. 11270 - 11271 (2009/02/05)
A novel chelate-controlled intermolecular oxidative Heck reaction is reported that proceeds with a wide range of nonresonance stabilized α-olefin substrates and organoboron reagents to afford internal olefin products in good yields and outstanding regio- and E:Z stereoselectivities. Pd-H isomerization, common in many Heck reactions, is not observed under these mild, oxidative conditions. This is evidenced by outstanding E:Z selectivities (>20:1 in all cases examined), no erosion in optical purity for proximal stereogenic centers, and a tolerance for unprotected alcohols. Remarkably, a single metal/ligand combination, Pd/bis-sulfoxide complex 1, catalyzes this reaction over a broad range of coupling partners. Given the high selectivities and broad scope, we anticipate this intermolecular Heck reaction will find heightened use in complex molecule synthesis. Copyright
