104941-05-1

Basic information

• Product Name: 1,2-bis(2,4-dichlorophenyl)prop-2-en-1-one
• Synonyms: 2-propen-1-one, 1,2-bis(2,4-dichlorophenyl)-
• CAS NO: 104941-05-1
• Molecular Formula: C₁₅H₈Cl₄O
• Molecular Weight: 346.0354
• Mol File: 104941-05-1.mol

Chemical Properties

• Boiling Point: 481.4°C at 760 mmHg
• Flash Point: 202.1°C
• Density: 1.427g/cm³
• Vapor Pressure: 1.99E-09mmHg at 25°C
• Refractive Index: 1.618
• CAS DataBase Reference: 1,2-bis(2,4-dichlorophenyl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis(2,4-dichlorophenyl)prop-2-en-1-one(104941-05-1)
• EPA Substance Registry System: 1,2-bis(2,4-dichlorophenyl)prop-2-en-1-one(104941-05-1)

Safety Data

• Hazardous Substances Data: 104941-05-1(Hazardous Substances Data)

Usage

Physical state at room temperature

Yellow solid

Solubility in water

Insoluble

Usage

Pesticide

Mode of action

Disrupts the nervous system of insects

Toxicity

Toxic to humans

Potential health effects

Causes irritation to skin, eyes, and respiratory system

Safety precautions

Follow all safety guidelines and regulations when handling

Upstream product

• 53056-20-5 2,4-dichlorophenylacetyl chloride 
• 541-73-1 1,3-Dichlorobenzene 
• 51-80-9 bis-(dimethylamino)methane 
• 107680-34-2 2-(2,4-dichlorophenyl)-2',4'-dichloroacetophenone 

Downstream Products

• 113193-66-1 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)-2',4'-dichloropropiophenone 
• 94171-15-0 (R)-(-)-1,2-bis(2,4-dichlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propan-1-one 
• 107741-26-4 (S)-(+)-1,2-bis(2,4-dichlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propan-1-one 
• 94171-15-0 2-(2,4-dichlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)-2',4'-dichloropropiophenone 
• 107659-41-6 (1R,2S)-1,2-bis(2,4-dichlorophenyl)-2,3-epoxypropan-1-ol 
• 107659-39-2 (1S,2R)-1,2-bis(2,4-dichlorophenyl)-2,3-epoxypropan-1-ol 
• 94147-83-8 (2,4-Dichloro-phenyl)-[(S)-2-(2,4-dichloro-phenyl)-oxiranyl]-methanone 
• 94147-83-8 (2,4-Dichloro-phenyl)-[(R)-2-(2,4-dichloro-phenyl)-oxiranyl]-methanone 
• 107659-42-7 (R)-1,2-Bis-(2,4-dichloro-phenyl)-prop-2-en-1-ol 
• 107659-40-5 (S)-1,2-bis(2,4-dichlorophenyl)prop-2-en-1-ol 
• 107659-43-8 (R)-(-)-1,2-bis(2,4-dichlorophenyl)-2-<(4-bromobenzoyl)-oxy>-3-(1H-1,2,4-triazol-1-yl)propan-1-one 
• 107659-73-4 (4S,5R)-4,5-Bis-(2,4-dichloro-phenyl)-4-[1,2,4]triazol-1-ylmethyl-[1,3]dioxolan-2-one 
• 107659-45-0 (1R,2S)-1,2-Bis-(2,4-dichloro-phenyl)-3-[1,2,4]triazol-1-yl-propane-1,2-diol 
• 94146-95-9 1,2-Bis-(2,4-dichloro-phenyl)-2-hydroxy-3-[1,2,4]triazol-4-yl-propan-1-one 

Relevant articles and documents

Synthesis and Antifungal Activity of a Series of Novel 1,2-Disubstituted Propenones

To find an antifungal agent other than those of the imidazole and triazole series, a new class of 1,2-disubstituted propenones I and II was prepared and tested for antifungal activity.Comparison of the structure-activity relationships showed that the conjugated structure of carbonyl and exomethylene groups in I and II plays an important role in potent antifungal acivity.However, it is noteworthy that compounds 53, 54, and 56, which have a hydroxymethyl or methoxymethyl group instead of an exo-methylene group in I, also showed potent activity.Although many compounds exhibited strong antifungal activity in vitro, none showed activity in vivo of oral efficacy against subacute systemic candidiasis in mice. '

A CONVENIENT SYNTHESIS OF 1H-1,2,4-TRIAZOL-1-YL-PROPAN-3-ONE DERIVATIVES BY MODIFIED MANNICH REACTION

1H-1,2,4-Triazol-yl-propan-3-ones were synthesized regioselectively using a modified Mannich reaction.Reactions of enones and Mannich bases with imidazole are also described.