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2-(3-Fluoro-2-nitrophenyl)acetonitrile is a chemical compound that features a phenyl ring with a fluorine atom, a nitro group, and a cyanide group. It is classified as a nitrile and an aromatic halogen compound, with an acetonitrile moiety that consists of a carbon atom triple-bonded to a nitrogen atom and single-bonded to a methyl group. 2-(3-Fluoro-2-nitrophenyl)acetonitrile is primarily used in research and development and requires careful handling and storage due to its reactive properties. 2-(3-Fluoro-2-nitrophenyl)acetonitrile's specific characteristics, such as boiling point, melting point, and toxicity, are subject to variation and should be obtained from comprehensive chemical databases.

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  • 105003-88-1 Structure
  • Basic information

    1. Product Name: 2-(3-Fluoro-2-nitrophenyl)acetonitrile
    2. Synonyms: 2-(3-Fluoro-2-nitrophenyl)acetonitrile
    3. CAS NO:105003-88-1
    4. Molecular Formula: C8H5FN2O2
    5. Molecular Weight: 180.1359032
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 105003-88-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(3-Fluoro-2-nitrophenyl)acetonitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(3-Fluoro-2-nitrophenyl)acetonitrile(105003-88-1)
    11. EPA Substance Registry System: 2-(3-Fluoro-2-nitrophenyl)acetonitrile(105003-88-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 105003-88-1(Hazardous Substances Data)

105003-88-1 Usage

Uses

Used in Chemical Research and Development:
2-(3-Fluoro-2-nitrophenyl)acetonitrile is utilized as a chemical intermediate for the synthesis of various organic compounds and pharmaceuticals. Its unique structure, which includes a fluorine atom, a nitro group, and a cyanide group, makes it a valuable building block in the development of new chemical entities with potential applications in medicine, materials science, and other fields.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(3-Fluoro-2-nitrophenyl)acetonitrile is used as a key intermediate in the synthesis of drugs with diverse therapeutic applications. Its presence in the molecular structure can influence the pharmacokinetic and pharmacodynamic properties of the resulting compounds, potentially leading to improved efficacy, selectivity, and safety profiles.
Used in Materials Science:
2-(3-Fluoro-2-nitrophenyl)acetonitrile can also be employed in the field of materials science, where it may contribute to the development of novel materials with specific properties. Its incorporation into polymers or other materials can result in altered physical, chemical, or electronic characteristics, which can be exploited in various applications, such as sensors, coatings, or advanced materials for electronics.

Check Digit Verification of cas no

The CAS Registry Mumber 105003-88-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,0,0 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 105003-88:
(8*1)+(7*0)+(6*5)+(5*0)+(4*0)+(3*3)+(2*8)+(1*8)=71
71 % 10 = 1
So 105003-88-1 is a valid CAS Registry Number.

105003-88-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(3-Fluoro-2-nitrophenyl)acetonitrile

1.2 Other means of identification

Product number -
Other names 2-(3-fluoro-2-nitrophenyl)acetonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105003-88-1 SDS

105003-88-1Downstream Products

105003-88-1Relevant articles and documents

Specific ortho-Cyanomethylation of Nitroarenes via the Vicarious Nucleophilic Substitution of Hydrogen

Makosza, Mieczyslaw,Wenaell, Maria,Golinski, Miroslaw,Kinowski, Andrzej

, p. 427 - 432 (2007/10/02)

The vicarious nucleophilic substitution of hydrogen in nitroarenes with acetonitrile derivatives XCH2CN in t-BuOK/THF base/solvent system proceeds exclusively ortho to the nitro group.Strong influence of substituents Z in 3-Z-nitrobenzene derivatives on the orientation has been observed.

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