Welcome to LookChem.com Sign In|Join Free

CAS

  • or
3-chloro-pyridine-2,5-dicarboxylic acid diMethyl ester is a chemical compound with the molecular formula C10H8ClNO4. It is a derivative of pyridine carboxylic acid, characterized by the presence of two methyl ester groups and a chlorine atom at the 3-position on the pyridine ring. 3-chloro-pyridine-2,5-dicarboxylic acid diMethyl ester is commonly utilized in the pharmaceutical industry for the synthesis of various drugs and biologically active compounds due to its unique structural features and potential biological activities.

106014-21-5 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 106014-21-5 Structure
  • Basic information

    1. Product Name: 3-chloro-pyridine-2,5-dicarboxylic acid diMethyl ester
    2. Synonyms: 3-chloro-pyridine-2,5-dicarboxylic acid diMethyl ester;DiMethyl 3-chloropyridine-2,5-dicarboxylate
    3. CAS NO:106014-21-5
    4. Molecular Formula: C9H8ClNO4
    5. Molecular Weight: 229.61712
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 106014-21-5.mol
  • Chemical Properties

    1. Melting Point: 126.0-127.0 °C
    2. Boiling Point: 331.8±37.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.347±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. PKA: -2.94±0.10(Predicted)
    10. CAS DataBase Reference: 3-chloro-pyridine-2,5-dicarboxylic acid diMethyl ester(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-chloro-pyridine-2,5-dicarboxylic acid diMethyl ester(106014-21-5)
    12. EPA Substance Registry System: 3-chloro-pyridine-2,5-dicarboxylic acid diMethyl ester(106014-21-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 106014-21-5(Hazardous Substances Data)

106014-21-5 Usage

Uses

Used in Pharmaceutical Industry:
3-chloro-pyridine-2,5-dicarboxylic acid diMethyl ester is used as a key intermediate in the synthesis of various drugs and biologically active compounds. Its unique structural features, including the presence of a chlorine atom and two methyl ester groups, make it a versatile building block for the development of new pharmaceutical agents.
Used in Medicinal Chemistry Research:
3-chloro-pyridine-2,5-dicarboxylic acid diMethyl ester is employed as a starting material or a synthetic intermediate in medicinal chemistry research. Its potential biological activities and chemical properties make it a valuable compound for exploring new drug targets and developing novel therapeutic agents.
Used in Drug Development:
3-chloro-pyridine-2,5-dicarboxylic acid diMethyl ester is used in the development of drugs targeting various diseases and conditions. Its unique chemical structure and potential biological activities make it a promising candidate for the discovery of new therapeutic agents with improved efficacy and selectivity.
Used in Industrial Applications:
3-chloro-pyridine-2,5-dicarboxylic acid diMethyl ester may also find use in other industrial applications beyond the pharmaceutical industry. Its unique chemical properties and potential reactivity make it a candidate for use in the synthesis of other chemical compounds or as a component in various industrial processes.

Check Digit Verification of cas no

The CAS Registry Mumber 106014-21-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,0,1 and 4 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 106014-21:
(8*1)+(7*0)+(6*6)+(5*0)+(4*1)+(3*4)+(2*2)+(1*1)=65
65 % 10 = 5
So 106014-21-5 is a valid CAS Registry Number.

106014-21-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name dimethyl 3-chloropyridine-2,5-dicarboxylate

1.2 Other means of identification

Product number -
Other names dimethyl 3-chloro-2,5-pyridinedicarboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:106014-21-5 SDS

106014-21-5Downstream Products

106014-21-5Relevant articles and documents

Selective alkoxycarbonylation of 2,3-dichloropyridines

Bessard, Yves,Roduit, Jean Paul

, p. 393 - 404 (1999)

2,3-Dichloropyridines undergo a motto- or a dicarbonylation in the presence of carbon monoxide, an alcohol and a palladium catalyst, affording selectively either alkyl 3-chloropicolinates, or dialkyl pyridine-2,3- dicarboxylates in good yields, depending on the reaction conditions.

SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS

-

Page/Page column 111-112, (2009/04/25)

Disclosed are compounds of formula (I) which are bradykinin B1 receptor (B1R) antagonists. These compounds are useful to treat diseases or relieve adverse symptoms associated with inflammation and pain. The invention encompasses novel compounds and acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases involving inflammation and pain.

A New Synthesis of Lysergic Acid

Hendrickson, James B.,Wang, Jian

, p. 3 - 5 (2007/10/03)

(Equation presented) (±)-Lysergic acid (1) has been synthesized via an economical 8-step route from 4-bromoindole and isocinchomeronic acid without the need to protect the indole during the synthesis. Initial efforts to form the simpler 3-acylindole derivatives first and then cyclize these were unsuccessful in the cyclization step.

Process for preparing pyridinecarboxylic esters

-

, (2008/06/13)

A process for preparing pyridinecarboxylic esters of the general formula: wherein R1 is hydrogen, a C1-6-alkyl group, a C1-4-alkoxycarbonyl group, a C1-4-alkoxymethyl group or a fluorinated C1-6-alkyl group, R2 is a C1-4-alkyl group and X is chlorine or bromine. The pyridinecarboxylic esters are obtained by reacing the corresponding 2,3-dihalopyridines with carbon monoxide and a C1-4-alkanol in the presence of a weak base and a complex of palladium with a bis(diphenylphosphine). Pyridinecarboxylic esters are intermediates for preparing herbicides and drugs against fibrotic diseases.

Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuticals

-

, (2008/06/13)

Sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation, and their use as pharmaceuticals The invention relates to sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-N-oxides according to the formul

Sulfonamidocarbonyl pyridine-2-carboxesteramides and their pyridine-N-oxide compounds and their use as pharmaceuticals

-

, (2008/06/13)

The invention relates to sulfonamidocarbonylpyridine-2-carboxesteramides and their pyridine-N-oxides according to the formula I STR1 Said compounds are used as pharmaceuticals against fibrotic disorders, as fibrosuppressants and as inhibitors of proline h

SUBSTITUTED HETEROCYCLIC CARBOXAMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS

-

, (2008/06/13)

The invention relates to compounds of the formula I, to a process for their preparation and to their use as pharmaceuticals. The compounds are employed, in particular, as ester prodrugs of prolyl hydroxylase inhibitors for inhibiting collagen biosynthesis and as fibrosuppressive agents

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 106014-21-5