1062135-87-8

Basic information

• Product Name: 7-broMo-2,4-bis(Methylthio)iMidazo[2,1-f][1,2,4]triazine
• Synonyms: 7-broMo-2,4-bis(Methylthio)iMidazo[2,1-f][1,2,4]triazine
• CAS NO: 1062135-87-8
• Molecular Formula: C₇H₇BrN₄S₂
• Molecular Weight: 291.19128
• EINECS: -0
• Mol File: 1062135-87-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-broMo-2,4-bis(Methylthio)iMidazo[2,1-f][1,2,4]triazine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-broMo-2,4-bis(Methylthio)iMidazo[2,1-f][1,2,4]triazine(1062135-87-8)
• EPA Substance Registry System: 7-broMo-2,4-bis(Methylthio)iMidazo[2,1-f][1,2,4]triazine(1062135-87-8)

Safety Data

• Hazardous Substances Data: 1062135-87-8(Hazardous Substances Data)

Upstream product

• 254114-39-1 6,8-Bis(methylsulfanyl)imidazo[2,1-f][1,2,4]triazine 

Downstream Products

• 1192264-54-2 C₃₄H₃₆N₄O₄S₂ 
• 1192264-55-3 C₃₃H₃₅N₅O₄S 
• 1192264-59-7 C₃₂H₃₄N₆O₄ 
• 1192264-56-4 C₃₃H₃₅N₅O₆S 
• 1456712-33-6 (2S,3R,4R,5R)-4-(benzyloxy)-5-(benzyloxymethyl)-2-(2,4-bis(methylthio)imidazo[2,1-f][1,2,4]triazin-7-yl)-3-fluorotetrahydrofuran-2-ol 
• 1456712-48-3 7-((2S,3R,4R,5R)-4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)-4-ethoxy-2-(methylsulfonyl)imidazo[2,1-f][1,2,4]triazine 
• 1456712-49-4 2-azido-7-((2S,3R,4R,5R)-4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)-4-ethoxyimidazo[2,1-f][1,2,4]triazine 
• 1456712-34-7 (2S,3R,4R,5R)-7-(4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)-2,4-bis(methylthio)imidazo[2,1-f][1,2,4]-triazine 
• 1456712-35-8 (2S,3R,4R,5R)-7-(4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)-2-(methylthio)imidazo[2,1-f][1,2,4]-triazin-4-amine 
• 1456712-36-9 (2S,3R,4R,5R)-7-(-4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)-2-(methylsulfonyl)imidazo[2,1-f][1,2,4]triazin-4-amine 
• 1456712-37-0 (2S,3R,4R,5R)-7-(4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)imidazo[2,1-f][1,2,4]-triazine-2,4-diamine 
• 1456712-38-1 (2S,3R,4R,5R)-5-(2,4-diaminoimidazo[2,1-f][1,2,4]-triazin-7-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol 
• 1456712-41-6 (2S,3R,4R,5R)-7-(4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)imidazo[2,1-f][1,2,4]-triazine-4-amine 
• 1456712-43-8 7-((2S,3R,4R,5R)-4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)-2-fluoroimidazo[2,1-f][1,2,4]-triazin-4-amine 

Relevant articles and documents

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Compounds of formula I or a stereoisomer or pharmaceutically-acceptable salt thereof, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.

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Compounds having the formula (I), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof, [PLEASE INSERT CHEMICAL STRUCTURE HERE] (I) are useful as kinase modulators, including Btk modulation, wherein R1, R2, R4, Q, Y, A and D are as defined herein.