- Facile preparation of various heteroaromatic compounds via azatitanacyclopentadiene intermediates
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Coupling of acetylene, nitrile, and a titanium reagent, Ti(O-i-Pr) 4/2 i-PrMgCl, generated new azatitanacyclopentadienes in a highly regioselective manner. Their subsequent reaction with sulfonylacetylene afforded pyridyltitanium compounds, which, upon reaction with electrophiles, gave substituted pyridines virtually as a single isomer. When optically active nitriles were used in this reaction, chiral pyridines were obtained without loss of the enantiopurity. Alternatively, the azatitanacyclopentadiene prepared from an unsymmetrical acetylene reacted with an aldehyde or another nitrile to give furans or pyrroles having four different substituents again in a regioselective manner.
- Suzuki, Daisuke,Nobe, Youhei,Watai, Yuko,Tanaka, Ryoichi,Takayama, Yuuki,Sato, Fumie,Urabe, Hirokazu
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- α,α'-DIACYLSTILBENES (Z): UN NOUVEL EXEMPLE DE TAUTOMERIE CYCLE-CHAINE. DIACETALISATION EN MILIEU NEUTRE.
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Sensitized photooxygenation of various 2,5-dialkyl-3,4-diphenyl-cyclopentadienones 1 in ether led to the expected (Z)-α,α'-diacylstilbenes 3 uncontaminated by their (E)-isomers.Several of these derivatives, bearing reactive acyl groups, show a special beh
- Rigaudy, Jean,Cuong, Nguyen Kim,Baranne-Lafont, Joele,Duminy, Philippe,Chassagnard, Claude
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p. 1345 - 1354
(2007/10/02)
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