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6-Desfluoro-6-hydroxy Risperidone is a derivative of Risperidone, which is an atypical antipsychotic medication. It is an impurity found in Risperidone (R525000) and is characterized by its light yellow solid appearance. 6-Desfluoro-6-hydroxy Risperidone holds potential for various applications due to its chemical properties and association with Risperidone.

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  • 106266-11-9 Structure
  • Basic information

    1. Product Name: 6-Desfluoro-6-hydroxy Risperidone
    2. Synonyms: 6-Desfluoro-6-hydroxy Risperidone;6,7,8,9-Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one
    3. CAS NO:106266-11-9
    4. Molecular Formula: C23H28N4O3
    5. Molecular Weight: 408.49342
    6. EINECS: N/A
    7. Product Categories: Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 106266-11-9.mol
  • Chemical Properties

    1. Melting Point: 247-250°C
    2. Boiling Point: 614.2°C at 760 mmHg
    3. Flash Point: 325.2°C
    4. Appearance: /
    5. Density: 1.4g/cm3
    6. Vapor Pressure: 1.12E-15mmHg at 25°C
    7. Refractive Index: 1.701
    8. Storage Temp.: -20°C Freezer
    9. Solubility: Chloroform (Slightly, Heated), Methanol (Very Slightly)
    10. CAS DataBase Reference: 6-Desfluoro-6-hydroxy Risperidone(CAS DataBase Reference)
    11. NIST Chemistry Reference: 6-Desfluoro-6-hydroxy Risperidone(106266-11-9)
    12. EPA Substance Registry System: 6-Desfluoro-6-hydroxy Risperidone(106266-11-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 106266-11-9(Hazardous Substances Data)

106266-11-9 Usage

Uses

Used in Pharmaceutical Industry:
6-Desfluoro-6-hydroxy Risperidone is used as a research compound for understanding the effects and mechanisms of Risperidone. Its study can contribute to the development of improved antipsychotic medications and provide insights into the treatment of psychiatric disorders.
Used in Quality Control and Impurity Profiling:
In the pharmaceutical industry, 6-Desfluoro-6-hydroxy Risperidone is used as a reference material for quality control and impurity profiling of Risperidone. This helps ensure the safety, efficacy, and purity of the final drug product.
Used in Analytical Chemistry:
6-Desfluoro-6-hydroxy Risperidone can be used as a standard compound in analytical chemistry for the development and validation of methods to detect and quantify impurities in Risperidone drug products.
Used in Drug Synthesis:
As a derivative of Risperidone, 6-Desfluoro-6-hydroxy Risperidone may have potential applications in the synthesis of new drugs with improved pharmacological properties or reduced side effects. Its chemical structure can serve as a starting point for the development of novel antipsychotic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 106266-11-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,2,6 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 106266-11:
(8*1)+(7*0)+(6*6)+(5*2)+(4*6)+(3*6)+(2*1)+(1*1)=99
99 % 10 = 9
So 106266-11-9 is a valid CAS Registry Number.
InChI:InChI=1/C23H28N4O3/c1-15-18(23(29)27-10-3-2-4-21(27)24-15)9-13-26-11-7-16(8-12-26)22-19-6-5-17(28)14-20(19)30-25-22/h5-6,14,16,28H,2-4,7-13H2,1H3

106266-11-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[1-[2-(2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-3-yl)ethyl]piperidin-4-yl]-2H-1,2-benzoxazol-6-one

1.2 Other means of identification

Product number -
Other names 6-Desfluoro-6-hydroxy Risperidone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:106266-11-9 SDS

106266-11-9Downstream Products

106266-11-9Relevant articles and documents

Antibodies to risperidone haptens and use thereof

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Page/Page column 48; 49, (2017/09/26)

Disclosed is an antibody which binds to risperidone, which can be used to detect risperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of risperidone, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.

Antibodies to Risperidone Haptens and Use Thereof

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Page/Page column, (2014/03/24)

Disclosed is an antibody which binds to risperidone, which can be used to detect risperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of risperidone, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.

HAPTENS OF RISPERIDONE AND PALIPERIDONE

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Page/Page column 51; 52, (2014/03/25)

The invention relates to compounds of Formula (I), wherein R1 and R2 are defined in the specification, useful for the synthesis of novel conjugates and imrnunogens derived from risperidone and paliperidone. The invention also relates to conjugates of a risperidone or paliperidone hapten and a protein.

3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles

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, (2008/06/13)

3-Piperdinyl-1,2-benzisothiazoles and 3-piperidinyl-1,2-benzisoxazoles and their pharmaceutically acceptable acid addition salts having useful antipsychotic properties and being useful in the treatment of a variety of complaints in which serotonin release is of predominant importance.

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