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1065267-25-5

1-(3,5-difluoropyridin-2-yl)ethanaMine hydrochloride is a pyridine derivative chemical compound widely utilized in pharmaceutical research and development. It serves as a crucial building block or intermediate in the synthesis of a variety of drugs, with its hydrochloride salt form being favored for its enhanced stability and solubility, facilitating easier handling and formulation in pharmaceutical preparations.

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  • 1065267-25-5 Structure

  • Basic information

    1. Product Name: 1-(3,5-difluoropyridin-2-yl)ethanaMine hydrochloride
    2. Synonyms: 1-(3,5-difluoropyridin-2-yl)ethanaMine hydrochloride
    3. CAS NO:1065267-25-5
    4. Molecular Formula: C7H9ClF2N2
    5. Molecular Weight: 194.6095664
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1065267-25-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(3,5-difluoropyridin-2-yl)ethanaMine hydrochloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(3,5-difluoropyridin-2-yl)ethanaMine hydrochloride(1065267-25-5)
    11. EPA Substance Registry System: 1-(3,5-difluoropyridin-2-yl)ethanaMine hydrochloride(1065267-25-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1065267-25-5(Hazardous Substances Data)

1065267-25-5 Usage

Uses

Used in Pharmaceutical Research and Development:
1-(3,5-difluoropyridin-2-yl)ethanaMine hydrochloride is used as a key intermediate for the synthesis of various drugs, contributing to the development of new medications with potential applications in treating a range of diseases and conditions.
Used in Drug Synthesis:
In the pharmaceutical industry, 1-(3,5-difluoropyridin-2-yl)ethanaMine hydrochloride is employed as a building block in the creation of novel drug molecules, leveraging its chemical properties to enhance the therapeutic potential and efficacy of resulting pharmaceuticals.
Used in Medicinal Chemistry:
1-(3,5-difluoropyridin-2-yl)ethanaMine hydrochloride is utilized in medicinal chemistry for the design and optimization of drug candidates, taking advantage of its structural features to improve pharmacokinetic and pharmacodynamic properties of new chemical entities.
Used in Drug Formulation:
The hydrochloride salt form of 1-(3,5-difluoropyridin-2-yl)ethanaMine is used in drug formulation to improve the solubility and stability of pharmaceutical preparations, ensuring better bioavailability and therapeutic effectiveness of the final drug product.

Check Digit Verification of cas no

The CAS Registry Mumber 1065267-25-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,5,2,6 and 7 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1065267-25:
(9*1)+(8*0)+(7*6)+(6*5)+(5*2)+(4*6)+(3*7)+(2*2)+(1*5)=145
145 % 10 = 5
So 1065267-25-5 is a valid CAS Registry Number.

1065267-25-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(3,5-Difluoropyridin-2-yl)-ethanamine hydrochloride

1.2 Other means of identification

Product number -
Other names 1-[3,5-bis(tert-butyl)-4-hydroxyphenyl]-2-bromoethan-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1065267-25-5 SDS

1065267-25-5Relevant articles and documents

HETEROCYCLIC JAK KINASE INHIBITORS

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Page/Page column 83-84, (2010/04/27)

The present invention relates to compounds of Formula (I) and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds provide a treatment for myeloproliferative disorders and cancer

TRICYCLIC 2,4-DIAMIN0-L,3,5-TRIAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF CANCER AND MYELOPROLIFERATIVE DISORDERS

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, (2010/01/07)

The present invention relates to compounds of Formula (I): (I) and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds provide a treatment for myeloproliferative disorders and cancer.

PYRAZOLYL-AMINO-SUBSTITUTED PYRAZINES AND THEIR USE FOR THE TREATMENT OF CANCER

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Page/Page column 75, (2008/12/04)

The present invention relates to compounds of Formula (I): and to their pharmaceutical compositions, and to their methods of use. These novel compounds provide a treatment for myeloproliferative disorders and cancer.

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