- Synthetic method of acid compound
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The invention belongs to the field of organic synthesis, and particularly relates to a synthetic method of an acid compound. An acid anhydride compound and an alkyl bromide or a functionalized alkyl bromide are subjected to a cross-electrophilic coupling reaction to synthesize an acid compound, so that the application of the alkyl bromide in the cross-electrophilic coupling reaction is expanded, and a novel non-traditional method for chemically and selectively constructing a carbon-carbon bond through a decarburization process is provided. The synthesis method is simple, economic, green and environment-friendly, and has wider applicability or is suitable for large-scale production.
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Paragraph 0028-0032; 0059
(2020/08/25)
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- Process for the preparation of fatty acids
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The invention discloses a method for preparing fatty acid. The method comprises the following steps: providing a first reactant which is a furan compound containing an carbonyl group; providing a second reactant which is a compound containing a carboxyl group, an ester group or an anhydride group and can participate in a condensation reaction with the carbonyl group of the first reactant; allowingthe first reactant and the second reactant to participate in a first condensation reaction, and allowing a C=O bond of the carbonyl group of the first reactant to be connected with alpha carbon of the carbonyl group of the second reactant and to be converted into a C=C bond so as to form a condensation product; and carrying out a second-step reaction under hydrogen pressure in the presence of a co-catalytic system of a hydrogenation catalyst and Lewis acid, opening a furan ring of the condensation product, carrying out hydrodeoxygenation at the same time, removing all oxygen except for oxygenin the carboxyl group, and allowing a carbon chain to be saturated so as to obtain the fatty acid.
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Paragraph 0179-0206; 0248-0250
(2020/09/04)
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