1073371-98-8 Usage
Uses
Used in Organic Synthesis:
2,5-DICHLORO-3-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE is used as a key intermediate in organic synthesis, particularly for the formation of carbon-carbon bonds through cross-coupling reactions. Its reactivity and stability contribute to the efficient synthesis of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2,5-DICHLORO-3-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE is used as a building block for the development of new drugs. Its unique structure allows for the creation of diverse molecular frameworks, potentially leading to the discovery of novel therapeutic agents.
Used in Agrochemical Development:
2,5-DICHLORO-3-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE is also utilized in the agrochemical sector as a precursor for the synthesis of new pesticides and herbicides. Its chemical properties enable the design of effective and targeted agrochemicals for crop protection.
Used in Material Science:
In material science, 2,5-DICHLORO-3-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE is employed in the development of advanced materials with specific properties. Its incorporation into polymers and other materials can enhance their performance, such as thermal stability, mechanical strength, or electrical conductivity.
Used in Catalysis:
2,5-DICHLORO-3-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE has potential applications in catalysis due to its ability to act as a catalyst or a catalyst support. Its structural features can facilitate various chemical reactions, improving the efficiency and selectivity of catalytic processes.
Check Digit Verification of cas no
The CAS Registry Mumber 1073371-98-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,3,3,7 and 1 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1073371-98:
(9*1)+(8*0)+(7*7)+(6*3)+(5*3)+(4*7)+(3*1)+(2*9)+(1*8)=148
148 % 10 = 8
So 1073371-98-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H14BCl2NO2/c1-10(2)11(3,4)17-12(16-10)8-5-7(13)6-15-9(8)14/h5-6H,1-4H3
1073371-98-8Relevant articles and documents
Understanding the Activation of Air-Stable Ir(COD)(Phen)Cl Precatalyst for C-H Borylation of Aromatics and Heteroaromatics
Slack, Eric D.,Colacot, Thomas J.
supporting information, p. 1561 - 1565 (2021/02/20)
A newly developed robust catalyst [Ir(COD)(Phen)Cl] (A) was used for the C-H borylation of three dozen aromatics and heteroaromatics with excellent yield and selectivity. Activation of the catalyst was identified by the use of catalytic amounts of water, alcohols, etc., when B2pin2 was used in noncoordinating solvents, while for THF catalytic use of HBpin was required. The results were on par with the in situ based expensive system [Ir(OMe)(COD)]2/dtbbpy or Me4Phen.
Iridium-catalyzed C-H borylation of pyridines
Sadler, Scott A.,Tajuddin, Hazmi,Mkhalid, Ibraheem A. I.,Batsanov, Andrei S.,Albesa-Jove, David,Cheung, Man Sing,Maxwell, Aoife C.,Shukla, Lena,Roberts, Bryan,Blakemore, David C.,Lin, Zhenyang,Marder, Todd B.,Steel, Patrick G.
supporting information, p. 7318 - 7327 (2014/11/07)
The iridium-catalysed C-H borylation is a valuable and attractive method for the preparation of aryl and heteroaryl boronates. However, application of this methodology for the preparation of pyridyl and related azinyl boronates can be challenged by low reactivity and propensity for rapid protodeborylation, particularly for a boronate ester ortho to the azinyl nitrogen. Competition experiments have revealed that the low reactivity is due to inhibition of the active catalyst through coordination of the azinyl nitrogen lone pair at the vacant site on the iridium. This effect can be overcome through the incorporation of a substituent at C-2. Moreover, when this is sufficiently electron-withdrawing protodeborylation is sufficiently slowed to permit isolation and purification of the C-6 boronate ester. Following functionalization, reduction of the directing C-2 substituent provides the product arising from formal ortho borylation of an unhindered pyridine ring. This journal is the Partner Organisations 2014.
