Welcome to LookChem.com Sign In|Join Free

CAS

  • or
4-Amino-3-bromo-2-hydroxypyridine is a chemical compound with the molecular formula C5H5BrN2O. It is a derivative of pyridine and contains an amino group, a hydroxyl group, and a bromine atom attached to the pyridine ring. This versatile building block in organic synthesis is known for its functional groups and reactivity, making it a valuable intermediate in the preparation of drug molecules and an important component in the development of new pharmaceuticals.

107842-74-0 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 107842-74-0 Structure
  • Basic information

    1. Product Name: 4-Amino-3-bromo-2-hydroxypyridine
    2. Synonyms: 4-Amino-3-bromo-2-hydroxypyridine;2(1H)-Pyridinone, 4-amino-3-bromo-;4-Amino-3-bromopyridin-2-ol;4-amino-3-bromo-1H-pyridin-2-one
    3. CAS NO:107842-74-0
    4. Molecular Formula: C5H5BrN2O
    5. Molecular Weight: 189.01
    6. EINECS: N/A
    7. Product Categories: Pyridines
    8. Mol File: 107842-74-0.mol
  • Chemical Properties

    1. Melting Point: 255-258 °C
    2. Boiling Point: 284.7 °C at 760 mmHg
    3. Flash Point: 126 °C
    4. Appearance: /
    5. Density: 1.826 g/cm3
    6. Vapor Pressure: 0.00293mmHg at 25°C
    7. Refractive Index: 1.635
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    9. Solubility: N/A
    10. PKA: 10.00±0.10(Predicted)
    11. CAS DataBase Reference: 4-Amino-3-bromo-2-hydroxypyridine(CAS DataBase Reference)
    12. NIST Chemistry Reference: 4-Amino-3-bromo-2-hydroxypyridine(107842-74-0)
    13. EPA Substance Registry System: 4-Amino-3-bromo-2-hydroxypyridine(107842-74-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 107842-74-0(Hazardous Substances Data)

107842-74-0 Usage

Uses

Used in Pharmaceutical Synthesis:
4-Amino-3-bromo-2-hydroxypyridine is used as a key intermediate for the synthesis of pharmaceuticals, contributing to the development of new drug molecules due to its unique structural features and reactivity.
Used in Agrochemical Production:
In the agrochemical industry, 4-Amino-3-bromo-2-hydroxypyridine is utilized as a building block in the creation of various agrochemicals, playing a crucial role in the synthesis of compounds that can enhance crop protection and yield.
Used in Organic Compounds Synthesis:
4-Amino-3-bromo-2-hydroxypyridine serves as a versatile building block in the synthesis of a wide range of organic compounds, leveraging its functional groups to form diverse molecular structures with potential applications across various industries.
Used in Heterocyclic Compounds Production:
4-Amino-3-bromo-2-hydroxypyridine is also used as a valuable intermediate in the production of heterocyclic compounds, which are important in various fields such as medicine, materials science, and chemical research, due to their diverse chemical properties and potential applications.

Check Digit Verification of cas no

The CAS Registry Mumber 107842-74-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,8,4 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 107842-74:
(8*1)+(7*0)+(6*7)+(5*8)+(4*4)+(3*2)+(2*7)+(1*4)=130
130 % 10 = 0
So 107842-74-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H5BrN2O/c6-4-3(7)1-2-8-5(4)9/h1-2H,(H3,7,8,9)

107842-74-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-amino-3-bromo-1H-pyridin-2-one

1.2 Other means of identification

Product number -
Other names 4-Amino-3-bromo-2-hydroxypyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:107842-74-0 SDS

107842-74-0Relevant articles and documents

Concise Entries to 4-Halo-2-pyridones and 3-Bromo-4-halo-2-pyridones

Honraedt, Aurélien,Gallagher, Timothy

, p. 67 - 69 (2016)

Methods for the synthesis of both simple 4-halo-2-pyridones and more functionalized 3,4-di- and (3,4,5-tri)-halo-2-pyridones are described that are based on a combination of Sandmeyer and regioselective (copper-mediated) halogenation, with a 2-chloro or a 2-benzyloxy moiety serving as a masked 2-pyridone.

Synthesis, Antitumor Activity, and Antiviral Activity of 3-Substituted 3-Deazacytidines and 3-Substituted 3-Deazauridines

McNamara, Dennis J.,Cook, P. Dan,Allen, Lois B.,Kehoe, Mary J.,Holland, Carolyn S.,Teepe, Annette G.

, p. 2006 - 2011 (2007/10/02)

Novel 3-substituted analogues of 4-amino-1-β-D-ribofuranosyl-2(1H)-pyridinone (3-deazacytidine, 3) and 4-hydroxy-1-β-D-ribofuranosyl-2(1H)-pyridinone (3-deazauridine, 4) have been synthesized and tested for antitumor and antiviral activity.Thus the 3-chloro (9a), 3-bromo (9b), and 3-nitro (9c) analogues of 3 and the 3-chloro (9d), 3-bromo (9e), and 3-nitro (9f) analogues of 4 were prepared by standard glycosylating procedures.Novel requisite heterocycles 4-amino-3-chloro-2(1H)-pyridinone (7a) and 4-amino-3-bromo-2(1H)-pyridinone (7b) were prepared by halogenating4-amino-2(1H)-pyridinone (5).Requisite heterocycles 4-amino-3-nitro-2(1H)-pyridinone (7c), 3-chloro-4-hydroxy-2(1H)-pyridinone (7d), 3-bromo-4-hydroxy-2(1H)-pyridinone (7e), and 4-hydroxy-3-nitro-2(1H)-pyridinone (7f) were synthesized by known procedures from 4-hydroxy-2(1H)-pyridinone (6).Structure proof of target nucleosides was provided by independent synthesis, 1H NMR, and UV.Compounds 9a-f were devoid of activity against intraperitoneally implanted L1210 leukemia in mice.Compound 9f displayed significant activity against rhinovirus type 34 grown in WISH cells. 4-Amino-3-fluoro-1-β-D-ribofuranosyl-2(1H)-pyridinone (1) displayed good activity against intraperitoneally implanted P388 leukemia in mice, but it was devoid of activity against M5076 sarcoma, amelanotic (LOX) melanoma xenograft, and subrenal capsule human mammary carcinoma MX-1 xenograft in mice.Compound 1 also displayed significant activity against rhinovirus type 34.

4-amino-3-halo-2-pyridinone nucleoside and nucleotide compounds

-

, (2008/06/13)

4-Amino-3-halo-1-β-D-ribofuranosyl-2-(1H)-pyridinone, 4-amino-3-halo-1-(2-deoxy-β-D-pentofuranosyl)-2(1H)-pyridinone, and nucleosides and 4-amino-3-halo-1-(2-deoxy-2,2-difluoroβ-D-pentofuranosyl)-2(1H)-pyridinone nucleosides and nucleotides are useful as antiviral agents and possess in vivo activity against the L1210 murine leukemia cell line.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 107842-74-0