107952-04-5

Basic information

• Product Name: 5-[(2-methoxyphenoxy)methyl]-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
• Synonyms: 4H-1,2,4-triazole-3-thiol, 5-[(2-methoxyphenoxy)methyl]-4-phenyl-
• CAS NO: 107952-04-5
• Molecular Formula: C₁₆H₁₅N₃O₂S
• Molecular Weight: 313.3742
• Mol File: 107952-04-5.mol

Chemical Properties

• Boiling Point: 435.1°C at 760 mmHg
• Flash Point: 216.9°C
• Density: 1.27g/cm³
• Vapor Pressure: 8.99E-08mmHg at 25°C
• Refractive Index: 1.64
• CAS DataBase Reference: 5-[(2-methoxyphenoxy)methyl]-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(2-methoxyphenoxy)methyl]-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione(107952-04-5)
• EPA Substance Registry System: 5-[(2-methoxyphenoxy)methyl]-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione(107952-04-5)

Safety Data

• Hazardous Substances Data: 107952-04-5(Hazardous Substances Data)

Upstream product

• 90-05-1 2-methoxy-phenol 
• 107967-88-4 ortho-anisoxyacetic acid hydrazide 
• 13078-21-2 ethyl 2-(2-methoxyphenoxy)acetate 
• 107951-92-8 C₁₆H₁₇N₃O₃S 

Relevant articles and documents

Synthesis of Some New Substituted Mercaptotriazoles and Thiazolidones and Their Monoamine Oxidase Inhibitory and Anticonvulsant Properties

A number of 4-aryl-5-aryloxymethyl-3-mercapto-1,2,4(H)-triazoles (IV) and 2-arylimino-3-aryloxyacetamido-4-thiazolidones (V) have been synthesized.Some of these compounds inhibit rat brain monoamine oxidase (MAO) in vitro at a final concentration of 1E-3 mol/litre, but are found to be inactive against pentylenetetrazole induced seizures in mice at a dose of 80 mg/kg.

Synthesis of some New Substituted Thiosemicarbazides and Triazoles as Possible Anticonvulsants

Forteen 1-o/p-anisoxyacetyl-4-arylthiosemicarbazides and their corresponding 5-(o/p-anisoxymethyl)-4-aryl-3-mercapto-1,2,4(H)-triazoles were synthesized.Eight of these compounds, when screened against maximal electroshock and pentylenetetrazole-induced seizures in mice at a dose of 80 mg/kg were, however, found to be inactive.