1079649-94-7

Basic information

• Product Name: 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyriMidin-7-one
• Synonyms: 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyriMidin-7-one;2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d];7H-Pyrrolo[3,4-d]pyriMidin-7-one, 2,4-dichloro-5,6-dihydro-6-(1-Methylethyl)-;2,4-DICHLORO-6-ISOPROPYL-5H-PYRROLO[3,4-D]PYRIMIDIN-7(6H)-ONE
• CAS NO: 1079649-94-7
• Molecular Formula: C₉H₉Cl₂N₃O
• Molecular Weight: 246.09326
• EINECS: -0
• Mol File: 1079649-94-7.mol

Chemical Properties

• Boiling Point: 422.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.460±0.06 g/cm3(Predicted)
• PKA: -4.59±0.20(Predicted)
• CAS DataBase Reference: 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyriMidin-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyriMidin-7-one(1079649-94-7)
• EPA Substance Registry System: 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyriMidin-7-one(1079649-94-7)

Safety Data

• Hazardous Substances Data: 1079649-94-7(Hazardous Substances Data)

Usage

Uses

Used in Agricultural Industry:
2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyrimidin-7-one is used as a herbicide for controlling broadleaf weeds in various crops. It is particularly effective in crops such as wheat, corn, and soybeans, where it helps to protect the plants from the detrimental effects of weeds that compete for nutrients, water, and sunlight.
The application reason for using 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyrimidin-7-one as a herbicide lies in its ability to disrupt the growth process of the weeds. It targets specific physiological processes within the weeds, inhibiting their growth and ultimately leading to their death. This selective action allows the crop plants to thrive without competition from the weeds, resulting in increased crop yields and improved agricultural productivity.
However, it is crucial to handle and apply this chemical with care, as exposure to high doses can be harmful to human health. Therefore, proper safety precautions should be taken when using 2,4-Dichloro-6-isopropyl-5,6-dihydropyrrolo[3,4-d]pyrimidin-7-one. This includes following the recommended application rates, using appropriate protective equipment, and adhering to the guidelines provided by regulatory authorities to minimize the risk of exposure and potential adverse effects.

Upstream product

• 65-86-1 orotic acid 
• 4156-75-6 2,4-dihydroxyfuro[3,4-d]pyrimidin-7(5H)-one 
• 1079649-91-4 2,4-dihydroxy-6-isopropyl-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one 
• 6341-93-1 orotic acid 

Downstream Products

• 1079658-41-5 benzyl (2R)-1-[4-(4-acetylpiperazin-1-yl)-7-oxo-8-propan-2-yl-3,5,8-triazabicyclo[4.3.0]nona-1,3,5-trien-2-yl]pyrrolidine-2-carboxylate 
• 1079651-60-7 2-chloro-4-{[2-(4-chlorophenyl)-1,1-dimethylethyl]amino}-6-isopropyl-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one 
• 1079652-11-1 2-chloro-4-[2-(4-fluoro-phenyl)-1,1-dimethyl-ethylamino]-6-isopropyl-5,6-dihydro-pyrrolo[3,4-d]pyrimidin-7-one 
• 1079657-78-5 2-(4-acetylpiperazin-1-yl)-6-isopropyl-4-(2-methoxy-4-(trifluoromethoxy)benzylamino)-5H-pyrrolo[3,4-d]pyrimidin-7(6H)-one 
• 1079655-48-3 C₂₅H₃₄N₆O₃ 
• 1079656-65-7 (S)-2-(4-acetylpiperazin-1-yl)-4-(1-(4-ethoxyphenyl)-2,2,2-trifluoroethylamino)-6-isopropyl-5H-pyrrolo[3,4-d]pyrimidin-7(6H)-one 
• 1079656-36-2 (R)-2-(4-acetylpiperazin-1-yl)-4-(1-(4-ethoxy-3-fluorophenyl)ethylamino)-6-isopropyl-5H-pyrrolo[3,4-d]pyrimidin-7(6H)-one 
• 1079664-08-6 C₂₂H₂₈N₆O₂ 
• 1079664-02-0 C₂₃H₃₀N₆O₂ 
• 1079653-89-6 C₂₃H₂₉ClN₆O₂ 
• 1079653-92-1 C₂₄H₃₂N₆O₂ 
• 1079653-27-2 C₂₄H₃₁ClN₆O₂ 
• 1079653-48-7 C₂₅H₃₃ClN₆O₂ 
• 1079653-46-5 C₂₆H₃₃ClN₆O₂ 

Relevant articles and documents

FUSED PYRIMIDINE COMPOUNDS AS KCC2

The invention concerns compounds of Formula (I): (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R7 and ring A have any of the meanings hereinbefore defined in the description; process for their preparation; pharmaceutical compositions containing them and their use in treating KCC2 mediated diseases.

Discovery of P2X3 selective antagonists for the treatment of chronic pain

Purinergic receptor P2X3 has been linked to analgesia in a number of pre-clinical models of pain, and is expressed in the human pain perception pathway. Only few P2X3-selective antagonists have been reported to date. This Letter describes the SAR and in vivo analgesic profile of a novel scaffold of selective P2X3 antagonists.

PYRROLOPYRIMIDIN-7-ONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

Compounds of formula (I) or pharmaceutically acceptable salts thereof wherein R1, R2, R3, R4, and R5 and are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.