108176-70-1 Usage
Uses
Used in Pharmaceutical Industry:
1-(2H-1,4-benzothiazin-3-yl)-3-(2,6-dimethylphenyl)urea is used as a potent and selective inhibitor for the enzyme DprE1, which is involved in the biosynthesis of the mycobacterial cell wall. Its inhibitory activity against DprE1 makes it a potential drug candidate for the treatment of tuberculosis, leprosy, and other mycobacterial infections. 1-(2H-1,4-benzothiazin-3-yl)-3-(2,6-dimethylphenyl)urea's ability to target and inhibit DprE1 can lead to the development of new therapeutic agents for the treatment of these infectious diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 108176-70-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,1,7 and 6 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 108176-70:
(8*1)+(7*0)+(6*8)+(5*1)+(4*7)+(3*6)+(2*7)+(1*0)=121
121 % 10 = 1
So 108176-70-1 is a valid CAS Registry Number.
108176-70-1Relevant articles and documents
Synthesis and Biological Activity of Some New N-(2H-1,4-benzoxazin- and benzothiazin-3-yl)-N'-arylureas
Shridhar, D. R.,Sastry, C. V. Reddy,Bansal, O. P.,Rao, P. Pulla
, p. 874 - 876 (2007/10/02)
A series of new N-(2H-1,4-benzoxazin- and benzothiazin-3-yl)-N'-arylureas (IV) and N-(4-methyl-2H-1,4-benzothiazinylidin-3-yl)-N'-arylureas (V) have been synthesised and screened for antiinflammatory, CNS, anthelmintic, antiprotozoal and antimicrobial activities.Some of the compounds possess a low order of antiinflammatory and mild CNS depressant activities.
