108249-43-0

Basic information

• Product Name: 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER
• Synonyms: 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER;RARECHEM AL BF 0099;Methyl 3-bromo-4-hydroxy-5-methoxybenzoate;Methyl 5-bromo-4-hydroxy-3-methoxybenzoate
• CAS NO: 108249-43-0
• Molecular Formula: C₉H₉BrO₄
• Molecular Weight: 261.07
• Mol File: 108249-43-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER(108249-43-0)
• EPA Substance Registry System: 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER(108249-43-0)

Safety Data

• Hazardous Substances Data: 108249-43-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER is used as a building block or intermediate in organic synthesis for its ability to contribute to the formation of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER is utilized as a key intermediate in the development of new drugs, capitalizing on its distinctive chemical properties to enhance drug efficacy and safety.
Used in Agrochemical Development:
3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER is employed in the creation of new agrochemicals, leveraging its potential to improve the effectiveness of agricultural products and contribute to sustainable farming practices.
Used as a Reagent or Catalyst in Chemical Reactions:
3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER also serves as a reagent or catalyst in various chemical processes, facilitating specific reactions and potentially increasing the yield or selectivity of desired products.

Upstream product

• 67-56-1 methanol 
• 6324-52-3 3-bromo-4-hydroxy-5-methoxybenzoic acid 
• 3943-74-6 4-hydroxy-3-methoxybenzoic acid methyl ester 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 

Downstream Products

• 175668-15-2 4-Acetoxy-3-bromo-5-methoxy-benzoic acid methyl ester 
• 23523-94-6 1-methoxy-3-methoxycarbonyl-9H-carbazole 
• 55182-57-5 2-Bromo-4-isopropylidene-6-methoxy-cyclohexa-2,5-dienone 
• 175668-18-5 4-Acetoxy-3-methoxy-5-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienyl)-benzoic acid methyl ester 

Relevant articles and documents

Bacterial Catabolism of Biphenyls: Synthesis and Evaluation of Analogues

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Double N-arylation of primary amines: Carbazole synthesis from 2,2′-biphenyldiols

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The biosynthesis of ubiquinone: Synthesis and enzymatic modification of biosynthetic precursors

The synthesis of key intermediates in the eukaryotic biosynthetic pathway of ubiquinone (Q) and the biotransformation of these materials with yeast (S.cerevisiae) mitochondria are described. The synthesis of Q aromatic precursors 2, 3, and 4 (n = 3 in all cases) relies on the palladium (0) catalyzed coupling of farnesyl tributylstannane with suitably functionalized aryl halides. Preliminary experiments show that incubation of synthetic substrate 3 with mitochondria from yeast containing the 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase gene (COQ3) and S-[methyl-3H]adenosyl-L-methionine yields radiolabeled 4.