108474-22-2 Usage
Uses
Used in Organic Synthesis:
4-(2,3-Dimethoxyphenyl)benzoic acid is used as a building block for the synthesis of various organic compounds. Its unique structure allows for the creation of a wide range of chemical entities, making it a versatile component in the development of new molecules with specific properties.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-(2,3-Dimethoxyphenyl)benzoic acid serves as an intermediate in the development of new drugs. Its potential biological and pharmacological properties make it a promising candidate for the creation of novel therapeutic agents.
Used in Drug Development:
4-(2,3-Dimethoxyphenyl)benzoic acid is utilized in the development of new drugs due to its potential to contribute to the pharmacological activity of the final product. Its structural features can be leveraged to enhance the efficacy and selectivity of drug candidates.
Used in Agrochemicals:
4-(2,3-Dimethoxyphenyl)benzoic acid also finds application in the field of agrochemicals, where it can be used to develop new pesticides or herbicides. Its unique structure may offer advantages in terms of selectivity and environmental impact, contributing to the development of more sustainable agricultural practices.
Check Digit Verification of cas no
The CAS Registry Mumber 108474-22-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,4,7 and 4 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 108474-22:
(8*1)+(7*0)+(6*8)+(5*4)+(4*7)+(3*4)+(2*2)+(1*2)=122
122 % 10 = 2
So 108474-22-2 is a valid CAS Registry Number.
108474-22-2Relevant articles and documents
Solid-phase Suzuki cross-coupling reactions using a phosphine ligand based on a phospha-adamantane framework
Ohnmacht, Stephan A.,Brenstrum, Tim,Bleicher, Konrad H.,McNulty, James,Capretta, Alfredo
, p. 5661 - 5663 (2007/10/03)
The use of a catalyst system based on Pd2dba3· CHCl3 and 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phospha- adamantane allows for Suzuki coupling aryl halides with an array of boronic acids on a solid-phase platform. The reactions can be carried out at room temperature with low palladium loadings in high yields.
Identification and initial structure-activity relationships of a novel class of nonpeptide inhibitors of blood coagulation factor Xa
Klein, Scott I.,Czekaj, Mark,Gardner, Charles J.,Guertin, Kevin R.,Cheney, Daniel L.,Spada, Alfred P.,Bolton, Scott A.,Brown, Karen,Colussi, Dennis,Heran, Christopher L.,Morgan, Suzanne R.,Leadley, Robert J.,Dunwiddie, Christopher T.,Perrone, Mark H.,Chu, Valeria
, p. 437 - 450 (2007/10/03)
The discovery and some of the basic structure-activity relationships of a series of novel nonpeptide inhibitors of blood coagulation Factor Xa is described. These inhibitors are functionalized β-alanines, exemplified by 2a. Docking experiments placing 2a in the active site of Factor Xa implied that the most expeditious route to enhancing in vitro potency was to modify the group occupying the S3 site of the enzyme. Increasing the hydrophobic contacts between the inhibitor and the enzyme in this region led to 8, which has served as the prototype for this series. In addition, an enantioselective synthesis of these substituted β-alanines was also developed.
