Synthesis and antimicrobial evaluation of new phenoxyacetamide derivatives
New N-(5-methylisoxazol-3-yl)-2 or 3 or 4-(phenoxyacetamido)benzamides 6a-t were synthesized and tested for their in vitro antimicrobial activity against gram positive (Staphylococcus aureus ATCC 25923) and gram negative (Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853) bacteria as well as fungi (Candida albicans ATCC 10231, Candida tropicalis ATCC 13803 and Cryptococcus neo-formans ATCC 90112). Compounds 6 were devoid of antibacterial as well as antifungal activities at maximum tested concentrations of 50 pg/ml for bacteria and 100 pg/ml for yeast.
Raffa,Migliara,Daidone,Maggio,Schiilaci
p. 3 - 7
(2007/10/03)
Synthesis of 1-(5-methylisoxazole-3-yl)-5-aryl-tetrazoles and its pyrolysis
3-Aroylamino-5-methylisoxazoles (2) were obtained by the reaction of 3- amino-5-methylisoxazole (1) with different aroyl chlorides. These amides on reaction with phosphorous pentachloride followed by sodium azide yielded 1- (5-methylisoxazole-3-yl)-5-aryl
Vasu, Kamala K.,Reddy, K. Kondal
p. 2847 - 2857
(2007/10/03)
Synthesis of Isoxazolyltetrazoles
Isoxazolyltetrazoles 6 and 9 have been synthesized by the reaction of 4-aroylamino- and 3-aroylaminoisoxazoles (4 and 8) with phosphorus pentachloride and azidolysis of the resulting imidoyl chlorides, respectively.The structures of these tetrazoles have
Prameela, B.,Rajanarendar, E.,Rao, C. Janakirama,Murthy, A. Krishna
p. 1209 - 1213
(2007/10/02)
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