1095708-32-9

Basic information

• Product Name: tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate
• Synonyms: tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate ;N-tert-butyl-N-[3-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbaMate;2-(tert-ButoxycarbonylaMino)pyridine-4-boronic acid pinacol ester;Boc-2-AMinopyridine-4-boronic acid pinacol ester;tert-butyl N-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbamate;[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-yl]-carbamic acid tert-butyl ester 97%;(2-((TERT-BUTOXYCARBONYL)AMINO)PYRIDIN-4-YL)BORONIC ACID PINACOL ESTER
• CAS NO: 1095708-32-9
• Molecular Formula: C₁₆H₂₅BN₂O₄
• Molecular Weight: 319.18376
• Mol File: 1095708-32-9.mol

Chemical Properties

• Boiling Point: 400.7±30.0 °C(Predicted)
• Appearance: /
• Density: 1.10
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 12.66±0.70(Predicted)
• CAS DataBase Reference: tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate(1095708-32-9)
• EPA Substance Registry System: tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate(1095708-32-9)

Safety Data

• Hazardous Substances Data: 1095708-32-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbamate is used as a building block in organic synthesis for the creation of various complex organic molecules. Its dioxaborolane group facilitates Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds and the synthesis of a wide range of organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbamate is used as a key intermediate in the synthesis of new drug candidates. Its unique structure and reactivity make it a promising starting material for the development of novel therapeutic agents with potential applications in various medical fields.
Used in Agrochemical Development:
Tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbamate is also utilized in the agrochemical sector as a building block for the synthesis of new agrochemicals. Its potential to form various chemical structures makes it a valuable component in the development of innovative pesticides, herbicides, and other agricultural chemicals to improve crop protection and yield.

Upstream product

• 84249-14-9 2-amino-4-bromopyridine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1195995-72-2 4-(4,4,5 ,5-tetramethyl-1,3 ,2-dioxaborolan-2-yl)pyridin-2-amine 
• 207799-10-8 (4-bromopyridin-2-yl)-carbamic acid tert-butyl ester 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1616930-52-9 C₂₈H₂₇F₂N₅O₃ 
• 1616929-95-3 5-[5-(2-amino-pyridin-4-yl)-2-methyl-phenyl]-N-(2,6-difluoro-phenyl)-1-methyl-1H-pyrazole-3-carboxylic acid amide 
• 1429893-18-4 4-(2-phenyl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazin-3-yl)pyridin-2-amine 
• 1429893-61-7 tert-butyl [4-(2-phenylpyrazolo[1,5-a]pyrimidin-3-yl)pyridin-2-yl]carbamate 
• 1429893-21-9 4-(2-phenylpyrazolo[1,5-a]pyrimidin-3-yl)pyridin-2-amine 
• 1338581-58-0 4-[2-(4-fluorophenyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]pyridin-2-amine 
• 1208069-63-9 {4-[6-(5-benzylhexahydropyrrolo[3,4-c]pyrrol-2-yl)-2-methylimidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}methylamine 
• 1208069-60-6 {4-[6-(5-benzylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)-2-methylimidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}amine 
• 1350916-74-3 N-[2-[4-(aminomethyl)-1-piperidinyl]-3,4-difluorophenyl]-4-(2-amino-4-pyridinyl)-1H-imidazole-2-carboxamide 
• 1350918-11-4 C₃₇H₅₃F₂N₇O₆Si 
• 1350916-75-4 4-(2-amino-4-pyridinyl)-N-(2-(4-((dimethylamino)methyl)-1-piperidinyl)phenyl)-1H-imidazole-2-carboxamide 
• 1350918-13-6 tert-butyl 4-(2-(2-(4-((dimethylamino)methyl)piperidin-1-yl)phenylcarbamoyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)pyridin-2-ylcarbamate 

Relevant articles and documents

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The invention relates to 2-alkyl-6-cycloamino-3-(pyridin-4-yl)imidazo[1,2-b]pyridazine derivatives of the general formula (I) where: R2 is a C1-6-alkyl, C3-7-cycloalkyl, C3-7-cycloalkyl-C1-4-alkyl, C1-4-alkyloxy-C-M-alkyl, C3-7-cycloalkyloxy-C1-4-alkyl>C3-7-cycloalkyl-C1-4-alkyloxy-C1-4-alkyl, hydroxy-C1-6-alkyl, C1-4-fluoroalkyl group; R3 is a hydrogen atom or a substituent selected from halogen atoms and the C1-3 alkyl, —NR4R5, hydroxyl or C1-4 alkyloxy groups; A is a C1-7-alkylene group optionally substituted by one or two Ra groups; B is a C1-7-alkylene group optionally substituted by one or two Rb groups; L is either a nitrogen atom optionally substituted by an Rc or Rd group or a carbon atom substituted by an Re1 group and an Rd group or by two Re2 groups; Rd is a group selected from a hydrogen atom or a C1-6-alkyl, C3-7-cycloalkyl, C3-7-cycloalkyl-C1-6-alkyl, C1-6-alkylthio-C1-6-alkyl, C1-6-alkyloxy-C1-6-alkyl, C1-6-fluoroalkyl, hydroxy-C1-6-alkyl group; Rf is a C1-6-alkyl, C3-7-cycloalkyl, C3-7-cycloalkyl-C1-6-alkyl, C1-6-alkyloxy-C1-6-alkyl, C3-7-cycloalkyloxy-C1-4-alkyl, C3-7-cycloalkyl-C1-4-alkyloxy-C1-4-alkyl, hydroxy-C1-6-allyl, C1-6-fluoroalkyl or benzyl group. The invention also relates to a method for preparing same and to the therapeutic application thereof.